ABSTRACT Background Primary or persistent endodontic disease is caused by microbial biofilms that irritate the pulp and periapical tissues. Extensive microbiological analyses of these biofilms and their constituent pathogens have revealed their diversity and complexity.
Ashraf F. Fouad
wiley +1 more source
Genome-resolved analysis reveals successional dynamics and functional transitions in chicken gut archaea across the broiler growth cycle. [PDF]
Zhang YF +5 more
europepmc +1 more source
Using Mendelian randomization, TWAS/eQTL analysis, machine learning, and single‐cell RNA sequencing, this study identified gut microbiota taxa causally linked to type 2 diabetes, candidate mediator genes, and diagnostic markers (BEND7, BLVRA, C1orf85, and LAMC1).
Yu‐yang Chen +6 more
wiley +1 more source
Beyond genomes: functional signatures reveal evolutionary patterns across the tree of life. [PDF]
Muñoz-Mérida A, Muñoz-Pajares AJ.
europepmc +1 more source
Synergistic engineering of Casδ nuclease for robust genome editing
A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plants, with overall editing performance comparable to that of SpCas9 and other Cas12 nucleases.
Fanghui Ge +16 more
wiley +1 more source
Resistance of the Archaeal Community to a Severe Disturbance in an Extreme Alkaline Saline Soil. [PDF]
Navarro-Noya YE +5 more
europepmc +1 more source
Auxin response and PIN‐mediated transport in chlorophyte algae
Like multicellular plants, green algae respond to auxin and move it across their cells. However, their PIN‐like proteins do not act like plant auxin exporters, suggesting that basic auxin transport evolved early and specialized directional transport appeared later in plant evolution.
Adrijana Smoljan +11 more
wiley +1 more source
Recent advances in exploring the composition and evolution of the prokaryotic selenoproteome. [PDF]
Zhang Y, Wang S, Li H, Chen X.
europepmc +1 more source
The Role of Oxidative Stress in Periodontitis
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon +3 more
wiley +1 more source
Spatial and temporal variation in bacterial-archaeal community and niche differentiation of denitrifying anaerobic methane-oxidizing microbes in grass carp (<i>Ctenopharyngodon idellus</i>) aquaculture ponds of Northern China. [PDF]
Chen Y, Pan Z, Wu Z, Tian Z.
europepmc +1 more source

