Results 31 to 40 of about 76,623 (339)

Redox and Thiols in Archaea [PDF]

open access: yesAntioxidants, 2020
Low molecular weight (LMW) thiols have many functions in bacteria and eukarya, ranging from redox homeostasis to acting as cofactors in numerous reactions, including detoxification of xenobiotic compounds. The LMW thiol, glutathione (GSH), is found in eukaryotes and many species of bacteria.
Mamta Rawat, Julie A. Maupin-Furlow
openaire   +4 more sources

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

open access: yesCancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022
Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem   +6 more
wiley   +1 more source

The archaeal KEOPS complex possesses a functional Gon7 homolog and has an essential function independent of the cellular t6A modification level

open access: yesmLife, 2023
Kinase, putative Endopeptidase, and Other Proteins of Small size (KEOPS) is a multisubunit protein complex conserved in eukaryotes and archaea.
Pengju Wu   +8 more
doaj   +1 more source

Putative Nucleotide-Based Second Messengers in the Archaeal Model Organisms Haloferax volcanii and Sulfolobus acidocaldarius

open access: yesFrontiers in Microbiology, 2021
Research on nucleotide-based second messengers began in 1956 with the discovery of cyclic adenosine monophosphate (3′,5′-cAMP) by Earl Wilbur Sutherland and his co-workers.
Frank Braun   +4 more
doaj   +1 more source

Metabolism of halophilic archaea [PDF]

open access: yesExtremophiles, 2008
In spite of their common hypersaline environment, halophilic archaea are surprisingly different in their nutritional demands and metabolic pathways. The metabolic diversity of halophilic archaea was investigated at the genomic level through systematic metabolic reconstruction and comparative analysis of four completely sequenced species: Halobacterium ...
Tanja Oberwinkler   +9 more
openaire   +3 more sources

Ancestral Reconstructions Decipher Major Adaptations of Ammonia-Oxidizing Archaea upon Radiation into Moderate Terrestrial and Marine Environments

open access: yesmBio, 2020
Unlike all other archaeal lineages, ammonia-oxidizing archaea (AOA) of the phylum Thaumarchaeota are widespread and abundant in all moderate and oxic environments on Earth. The evolutionary adaptations that led to such unprecedented ecological success of
Sophie S. Abby   +2 more
doaj   +1 more source

tRNA-isoleucine-tryptophan Composite Gene [PDF]

open access: yesBiochemical and biophysical Research Communications 339 (2005) 37-40, 2005
Transfer-RNA genes in archaea often have introns intervening between exon sequences. The structural motif at the boundary between exon and intron is the bulge-helix-bulge. Computational investigations of these boundary structures in H. marismortui lead us to propose that tRNA-isoleucine and tRNA-tryptophan genes are co-located.
arxiv   +1 more source

CRISPR-Cas Adaptive Immune Systems of the Sulfolobales: Unravelling Their Complexity and Diversity

open access: yesLife, 2015
The Sulfolobales have provided good model organisms for studying CRISPR-Cas systems of the crenarchaeal kingdom of the archaea. These organisms are infected by a wide range of exceptional archaea-specific viruses and conjugative plasmids, and their ...
Roger A. Garrett   +11 more
doaj   +1 more source

Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2

open access: yesNature Communications, 2022
Single-molecule FRET measurements provide detailed insights into the conformational states and dynamics of human Argonaute 2 that are required for its function at the core of the eukaryotic RNA silencing pathway.
Sarah Willkomm   +6 more
doaj   +1 more source

Archaea in der Biotechnologie [PDF]

open access: yesBIOspektrum, 2021
AbstractArchaea are prokaryotic organisms with highly interesting physiological features. They have also shown potential for the production of biotechnological compounds. Today, the commercially available products of archaea are bacterioruberin, squalene, bacteriorhodopsin, and lipids — all of which are produced by utilizing halophilic archaea.
Bernhard Schuster   +5 more
openaire   +2 more sources

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