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The cell biology of archaea

open access: yesNature Microbiology, 2022
The past decade has revealed the diversity and ubiquity of archaea in nature, with a growing number of studies highlighting their importance in ecology, biotechnology and even human health. Myriad lineages have been discovered, which expanded the phylogenetic breadth of archaea and revealed their central role in the evolutionary origins of eukaryotes ...
van Wolferen, Marleen   +4 more
openaire   +4 more sources

The archaeal KEOPS complex possesses a functional Gon7 homolog and has an essential function independent of the cellular t6A modification level

open access: yesmLife, 2023
Kinase, putative Endopeptidase, and Other Proteins of Small size (KEOPS) is a multisubunit protein complex conserved in eukaryotes and archaea.
Pengju Wu   +8 more
doaj   +1 more source

Archaeal GPN-loop GTPases involve a lock-switch-rock mechanism for GTP hydrolysis

open access: yesmBio, 2023
Three GPN-loop GTPases, GPN1–GPN3, are central to the maturation and trafficking of eukaryotic RNA polymerase II. This GTPase family is widely represented in archaea but typically occurs as single paralogs.
Lukas Korf   +9 more
doaj   +1 more source

Metagenomes from Coastal Marine Sediments Give Insights into the Ecological Role and Cellular Features of Loki- and Thorarchaeota

open access: yesmBio, 2019
The genomes of Asgard Archaea, a novel archaeal proposed superphylum, share an enriched repertoire of eukaryotic signature genes and thus promise to provide insights into early eukaryote evolution.
Lokeshwaran Manoharan   +5 more
doaj   +1 more source

The canonical single-stranded DNA-binding protein is not an essential replication factor but an RNA chaperon in Saccharolobus islandicus

open access: yesiScience, 2023
Summary: Single-stranded DNA-binding proteins (SSBs) have been regarded as indispensable replication factors. Herein, we report that the genes encoding the canonical SSB (SisSSB) and the non-canonical SSB (SisDBP) in Saccharolobus islandicus REY15A are ...
Yuanxi Xiao   +12 more
doaj   +1 more source

Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2

open access: yesNature Communications, 2022
Single-molecule FRET measurements provide detailed insights into the conformational states and dynamics of human Argonaute 2 that are required for its function at the core of the eukaryotic RNA silencing pathway.
Sarah Willkomm   +6 more
doaj   +1 more source

CRISPR-Cas Adaptive Immune Systems of the Sulfolobales: Unravelling Their Complexity and Diversity

open access: yesLife, 2015
The Sulfolobales have provided good model organisms for studying CRISPR-Cas systems of the crenarchaeal kingdom of the archaea. These organisms are infected by a wide range of exceptional archaea-specific viruses and conjugative plasmids, and their ...
Roger A. Garrett   +11 more
doaj   +1 more source

Hyperthermophilic methanogenic archaea act as high-pressure CH4 cell factories

open access: yesCommunications Biology, 2021
Mauerhofer et al. examine 80 species of methanogenic archaea at high pressures and evaluate growth and methane production, identifying Methanotorris igneus and Methanocaldococcoccus jannaschii as high-pressure methane cell factories.
Lisa-Maria Mauerhofer   +9 more
doaj   +1 more source

Community dynamics of archaea in an estuarine river water column and implications for archaeal biogeochemistry

open access: yes, 2022
Shah Walter, SunitaIn the past three decades, it has been established that archaea play important biogeochemical roles in the marine water column and sediments, but there remains a gap in knowledge about the phenology of these marine planktic archaea ...
Guider, Justin
core   +1 more source

DPANN archaea [PDF]

open access: yesCurrent Biology
Archaea are one of the two primary domains of life alongside Bacteria. Extant archaea play an important role in global nutrient cycles and comprise members that were crucial for the evolution of life on Earth including the origin of eukaryotic cells through a symbiotic integration of an archaeal and bacterial partner.
Huang, W.-C., Spang, A.
openaire   +2 more sources

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