A comprehensive database for high-throughput identification of archaeal lipids using high-resolution mass spectrometry [PDF]
Nature CommunicationsArchaeal membrane lipids are markedly distinct from those in bacteria and eukaryotes, serving as biomarkers for unraveling their ecological and biogeochemical roles.
Fengfeng Zheng +12 more
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Identification of a protein responsible for the synthesis of archaeal membrane-spanning GDGT lipids
Nature Communications, 2022 The cell membranes of many archaea contain characteristic membrane-spanning lipids known as glycerol dibiphytanyl glycerol tetraethers. Here, Zeng et al.
Zhirui Zeng, Huan Yang, Wei Yang
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Engineering archaeal membrane‐spanning lipid GDGT biosynthesis in bacteria: Implications for early life membrane transformations [PDF]
mLifeEukaryotes are hypothesized to be archaeal–bacterial chimeras. Given the different chemical structures of membrane phospholipids in archaea and bacteria, transformations of membranes during eukaryogenesis that led to the bacterial‐type membranes of ...
Huahui Chen +9 more
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Archaeal lipids trace ecology and evolution of marine ammonia-oxidizing archaea [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2022 Yi Ge Zhang +2 more
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Uncovering the prevalence, key biogenesis enzymes, and biological significance of archaeal lipoproteins [PDF]
Nature CommunicationsLipid-anchored proteins are integral components of cell surfaces. In bacteria, lipidation of proteins with a conserved lipobox motif ([L/V/I]−3 [A/S/T/V/I]−2 [G/A/S]−1 [C]+1) is catalyzed by prolipoprotein diacylglyceryl transferase (Lgt).
Yirui Hong +6 more
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Microbial decomposer diversity and metabolic function during the decomposition of brine shrimp carcasses in a saline lake [PDF]
MicrobiomeBackground Decomposition of brine shrimp carcasses has a crucial role in carbon cycling of saline lakes, yet the microbial dynamics remain poorly understood.
Lei Gao +21 more
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Impacts of temperature and pH on the distribution of archaeal lipids in Yunnan hot springs, China [PDF]
Frontiers in Microbiology, 2013 In culture experiments and many low temperature environments, the distribution of isoprenoid glycerol dialkyl glycerol tetraethers (GDGTs) commonly shows a strong correlation with temperature; however, this is often not the case in hot springs.
Weiyan eWu +8 more
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Archaeosomes: New Generation of Liposomes Based on Archaeal Lipids for Drug Delivery and Biomedical Applications [PDF]
ACS Omega, 2023 Julia Genova, Poornima Budime Santhosh
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Archaeal Lipids Regulating the Trimeric Structure Dynamics of Bacteriorhodopsin for Efficient Proton Release and Uptake [PDF]
International Journal of Molecular Sciences, 2022 Xiao He, Xin Zhao, Anthony Watts
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Nanoarchaeosomes for synergistic photochemotherapy in triple-negative breast cancer [PDF]
Scientific ReportsTriple-negative breast cancer (TNBC) poses significant therapeutic challenges due to the lack of targetable receptors and the systemic toxicity associated with conventional treatments such as surgery, radiotherapy, and chemotherapy.
Shaik Sameer Basha +10 more
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