Results 21 to 30 of about 5,158 (166)

Structural and Functional Insights into an Archaeal Lipid Synthase [PDF]

Cell Reports, 2020
The UbiA superfamily of intramembrane prenyltransferases catalyzes an isoprenyl transfer reaction in the biosynthesis of lipophilic compounds involved in cellular physiological processes. Digeranylgeranylglyceryl phosphate (DGGGP) synthase (DGGGPase) generates unique membrane core lipids for the formation of the ether bond between the glycerol moiety ...
Sixue Ren, Niels A.W. de Kok, Yijun Gu, Weizhu Yan, Qiu Sun, Yunying Chen, Jun He, Lejin Tian, Ruben L.H. Andringa, Xiaofeng Zhu, Mei Tang, Shiqian Qi, Heng Xu, Haiyan Ren, Xianghui Fu, Adriaan J. Minnaard, Shengyong Yang, Wanjiang Zhang, Weimin Li, Yuquan Wei, Arnold J.M. Driessen, Wei Cheng   +21 more
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Archaeal lipids in oral delivery of therapeutic peptides [PDF]

European Journal of Pharmaceutical Sciences, 2017
Archaea contain membrane lipids that differ from those found in the other domains of life (Eukarya and Bacteria). These lipids consist of isoprenoid chains attached via ether bonds to the glycerol carbons at the sn-2,3 positions. Two types of ether lipids are known, polar diether lipids and bipolar tetraether lipids. The inherent chemical stability and
Ann-Christin Jacobsen, Sara M Jensen, Gert Fricker, Martin Brandl, Alexander H. Treusch   +4 more
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Resolving a piece of the archaeal lipid puzzle [PDF]

Proceedings of the National Academy of Sciences, 2019
Lipid membranes are common to all cells, despite occurring in many different forms across Earth’s great biotic diversity. Among the most distinctive membranes are those formed by the archaea, whose lipids are characterized by sn -2,3-glycerol stereochemistry (in contrast to sn -1,2-glycerol in bacteria and eukarya), isoprenoid rather than acetyl ...
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Structure and Phase Behavior of Archaeal Lipid Monolayers

Langmuir, 2011
We report X-ray reflectivity (XRR) and grazing incidence X-ray diffraction (GIXD) measurements of archaeal bipolar tetraether lipid monolayers at the air-water interface. Specifically, Langmuir films made of the polar lipid fraction E (PLFE) isolated from the thermoacidophilic archaeon Sulfolobus acidocaldarius grown at three different temperatures ...
Jeworrek, Christoph, Evers, Florian, Erlkamp, Mirko, Grobelny, Sebastian, Tolan, Metin, Chong, Parkson Lee-Gau, Winter, Roland   +6 more
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Activity of Ancillary Heterotrophic Community Members in Anaerobic Methane-Oxidizing Cultures

Frontiers in Microbiology, 2022
Consortia of anaerobic methanotrophic archaea (ANME) and sulfate-reducing bacteria mediate the anaerobic oxidation of methane (AOM) in marine sediments.
Qing-Zeng Zhu, Gunter Wegener, Gunter Wegener, Kai-Uwe Hinrichs, Kai-Uwe Hinrichs, Marcus Elvert, Marcus Elvert   +6 more
doaj   +1 more source

Osmotic shock induces the presence of glycocardiolipin in the purple membrane of Halobacterium salinarum

Journal of Lipid Research, 2003
In the purple membrane (PM) of Halobacterium salinarum is present a phospholipid dimer consisting of sulfo-triglycosyl-diether (S-TGD-1) esterified to the phosphate group of phosphatidic acid (PA), i.e., S-TGD-1-PA, called glycocardiolipin (GlyC ...
Simona Lobasso, Patrizia Lopalco, Veronica M.T. Lattanzio, Angela Corcelli   +3 more
doaj   +1 more source

Archaeal intact polar lipids in polar waters: a comparison between the Amundsen and Scotia seas [PDF]

Biogeosciences, 2021
The West Antarctic Ice Sheet (WAIS) is one of the largest potential sources of future sea-level rise, with glaciers draining the WAIS thinning at an accelerating rate over the past 40 years.
C. L. Spencer-Jones, E. L. McClymont, N. J. Bale, E. C. Hopmans, S. Schouten, S. Schouten, J. Müller, E. P. Abrahamsen, C. Allen, T. Bickert, C.-D. Hillenbrand, E. Mawbey, V. Peck, A. Svalova, J. A. Smith   +14 more
doaj   +1 more source

Heat Stress Dictates Microbial Lipid Composition along a Thermal Gradient in Marine Sediments

Frontiers in Microbiology, 2017
Temperature exerts a first-order control on microbial populations, which constantly adjust the fluidity and permeability of their cell membrane lipids to minimize loss of energy by ion diffusion across the membrane.
Miriam Sollich, Marcos Y. Yoshinaga, Marcos Y. Yoshinaga, Stefan Häusler, Roy E. Price, Roy E. Price, Kai-Uwe Hinrichs, Solveig I. Bühring   +7 more
doaj   +1 more source

A membrane-spanning macrocyclic bolaamphiphile lipid mimic of archaeal lipids [PDF]

Canadian Journal of Chemistry, 2017
The synthesis of a 72-membered macrocyclic tetraester bolaamphiphile is accomplished in six chemical steps from commercially available starting materials using copper-accelerated azide–alkyne coupling to close the macrocycle in high yield. Related diester amphiphiles and an acyclic tetraester bolaamphiphile were also prepared.
Mitchell, Gavin Maxwell, Hesketh, Amelia, Lombardi, Christie, Ho, Cally, Fyles, Thomas M.   +4 more
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The Role of Tetraether Lipid Composition in the Adaptation of Thermophilic Archaea to Acidity

Frontiers in Microbiology, 2013
Diether and tetraether lipids are fundamental components of the archaeal cell membrane. Archaea adjust the degree of tetraether lipid cyclization in order to maintain functional membranes and cellular homeostasis when confronted with pH and/or thermal ...
Eric eBoyd, Trinity eHamilton, Jinxiang eWang, Liu eHe, Chuanlun eZhang   +4 more
doaj   +1 more source