Results 61 to 70 of about 518 (150)

Effect of Growth Medium pH of Aeropyrum pernix on Structural Properties and Fluidity of Archaeosomes

Archaea, Volume 2012, Issue 1, 2012., 2012
The influence of pH (6.0; 7.0; 8.0) of the growth medium of Aeropyrum pernix K1 on the structural organization and fluidity of archaeosomes prepared from a polar‐lipid methanol fraction (PLMF) was investigated using fluorescence anisotropy and electron paramagnetic resonance (EPR) spectroscopy.
Ajda Ota, Dejan Gmajner, Marjeta Šentjurc, Nataša Poklar Ulrih, Parkson Chong   +4 more
wiley   +1 more source

Effect of Chiral Purity on Adjuvanticity of Archaeol-Based Glycolipids

, 2022
Archaeosomes composed of sulfated lactosyl archaeol (SLA) glycolipids from stereoisomerically pure archaeol (1) are vaccine adjuvants that can boost immunogenicity and vaccine efficacy in preclinical models. Herein, we report a new synthesis of 2,3-bis­((
Vinicio Vasquez (12770823), Blair A. Harrison (6041411), Michael J. McCluskie (9644822), Usha D. Hemraz (1692154), Renu Dudani (6041408), Gerard Agbayani (6041414), Edmond Lam (2686417), Lise Deschatelets (6041405), Bassel Akache (30143), Felicity C. Stark (12770826), Sophie Régnier (1566229), Camilo F. Martinez-Farina (1411444)   +11 more
core   +2 more sources

Surviving nebulization-induced Stress: Dexamethasone in pH-sensitive Archaeosomes

Nanomedicine, 2016
To increase the subcellular delivery of dexamethasone phosphate (DP) and stability to nebulization stress, pH-sensitive nanoliposomes (LpH) exhibiting archaeolipids, acting as ligands for scavenger receptors (pH-sensitive archaeosomes [ApH]), were prepared.The anti-inflammatory effect of 0.18 mg DP/mg total lipid, 100-150 nm DP-containing ApH ...
Altube, María Julia, Selzer, Solange Mailen, de Farias, Marcelo Alexandre, Portugal, Rodrigo Villares, Morilla, María José, Romero, Eder Lilia   +5 more
openaire   +3 more sources

Folate-conjugated stealth archaeosomes for the targeted delivery of novel antitumoral peptides

, 2016
International audienceIn this work, novel archaeosomes based on Egg-PC and a mixture of PEGylated archaeal tetraether lipids were investigated as nanocarriers for in vitro delivery of an original anticancer peptide.
Jiblaoui, A., Benvegnu, T., Barbeau, J., Glippa, V., Vivès, T., Cormier, P., Cosson, B.   +6 more
core   +1 more source

Phase contrast microscope images of archaeosomes composed of different mixtures of archaeabacterial lipids.

, 2013
Archaeosomes composed of different mixtures of archaebacterial lipids as indicated in individual panels. Panel A shows different regions in the same observation chamber.
Vid Šuštar (316735), Ajda Ota (316739), Angela Corcelli (222554), Veronika Kralj-Iglič (316740), Simona Lobasso (316738), Patrizia Lopalco (316737), Jasna Zelko (316736), Nataša Poklar Ulrih (155068)   +7 more
core   +1 more source

Archaeosomes as carriers for topical delivery of betamethasone dipropionate: in vitro skin permeation study

, 2009
A comparative study between archaeosomes, lipid lamellar vesicles made from archaea polar lipids, and conventional phospholipids liposomes was carried out, aiming at evaluating the properties and the potential of archaeosomes as novel colloidal carriers ...
Gonzalez Paredes A, Monteoliva Sanchez M, FADDA, ANNA MARIA, MANCONI, MARIA, Ramos Cormenzana A, CADDEO, CARLA, Maria Manconi, Carla Caddeo, Mercedes Monteoliva-Sánchez, Anna Maria Fadda, Alberto Ramos-Cormenzana, Ana González-Paredes   +11 more
core   +1 more source

Archaeosomes induce enhanced cytotoxic T lymphocyte responses to entrapped souble antigens in the absence of IL-12 and protect against tumor challenge.

, 2003
Archaeosome adjuvants formulated as archaeal ether glycerolipid vesicles induce strong CD4(+) as well as CD8(+) CTL responses to entrapped soluble antigens.
Sad, Subash, Patel, G., Sprott, G., Krishnan, Lakshmi   +3 more
core   +1 more source

Archaeosomes induce long-term CD8 + cytotoxic response to entrapped soluble protein by the exogenous cytosolic pathway, in the absence of CD4 + T cell help

, 2000
The unique ether glycerolipids of Archaea can be formulated into vesicles (archaeosomes) with strong adjuvant activity for MHC class II presentation.
Sad, Subash, Patel, G., Sprott, G., Krishnan, Lakshmi, Subash Sad, G. Dennis Sprott, Lakshmi Krishnan, Girishchandra B. Patel   +7 more
core   +1 more source

99mTc radiolabeled archaeosomes as a potential melanoma imaging agent

Proceedings of Anticancer Research, 2018
Background: Melanoma incidence is growing worldwide. Although recent advances in imaging, there isn`t still available a specific melanoma agent that can be used for melanoma staging. Archaeosomes may be defined as liposomes composed of one or more polar lipids extracted from the Archaea domain (Archaebacterium). Objective:  As liposomes have been used
Pablo Cabral, Mirel Cabrera, Marcos Tassano, Marcelo Fernadez, Juan Pablo Gambini   +4 more
openaire   +2 more sources

New generation of liposomes called archaeosomes based on natural or synthetic archaeal lipids as innovative formulations for drug delivery.

, 2009
International audienceArchaeosomes made from natural archaeal membrane lipids and/or synthetic lipid analogues have been extensively studied for potential applications in drug and vaccine delivery over the past decade only.
Cammas-Marion, Sandrine, Lemiègre, Loïc, Benvegnu, Thierry, Sandrine Cammas-Marion, Loic Lemiegre, Thierry Benvegnu   +5 more
core   +1 more source