Results 61 to 70 of about 478 (150)

Archaeosomes varying in lipid composition differ in receptor mediated endocytosis and differentially adjuvant immune responses to entrapped antigen [PDF]

, 2003
Archaeosomes prepared from total polar lipids extracted from six archaeal species with divergent lipid compositions had the capacity to deliver antigen for presentation via both MHC class I and class II pathways.
Sad, Subash, Dicaire, Chantal, Patel, G., Krisnan, L., Sprott, G., Fleming, L.   +5 more
core  

The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo

, 2001
The unique glycerolipids of Archaea can be formulated into vesicles (archaeosomes) with potent adjuvant activity. We studied the effect of archaeosomes on APCs to elucidate the mechanism(s) of adjuvant action.
Sad, Subash, Patel, G., Sprott, G., Krishnan, Lakshmi   +3 more
core   +1 more source

Physical Properties and Membrane Packing in Hybrid Archaeosomes [PDF]

Biophysical Journal, 2015
In this study, we have characterized the physical properties of liposomes made of archaeal bipolar tetraether lipids (BTL) and “conventional” monopolar diester lipids (termed as hybrid archaeosomes). We used the polar lipid fraction E (PLFE) isolated from the thermoacidophilic archaeon Sulfolobus acidocaldarius as the BTL component of the hybrid ...
Ayesa, Umme, Chong, Parkson L.G.
openaire   +1 more source

Archaeosomes as carriers for topical delivery of betamethasone dipropionate: in vitro skin permeation study

, 2010
A comparative study between archaeosomes, lipid lamellar vesicles made from archaea polar lipids, and conventional phospholipids liposomes was carried out, aiming at evaluating the properties and the potential of archaeosomes as novel colloidal carriers ...
Gonzalez Paredes A, Monteoliva Sanchez M, FADDA, ANNA MARIA, MANCONI, MARIA, Ramos Cormenzana A, CADDEO, CARLA   +5 more
core   +1 more source

99mTc radiolabeled archaeosomes as a potential melanoma imaging agent

Proceedings of Anticancer Research, 2018
Background: Melanoma incidence is growing worldwide. Although recent advances in imaging, there isn`t still available a specific melanoma agent that can be used for melanoma staging. Archaeosomes may be defined as liposomes composed of one or more polar lipids extracted from the Archaea domain (Archaebacterium). Objective:  As liposomes have been used
Pablo Cabral, Mirel Cabrera, Marcos Tassano, Marcelo Fernadez, Juan Pablo Gambini   +4 more
openaire   +2 more sources

Folate-conjugated stealth archaeosomes for the targeted delivery of novel antitumoral peptides

, 2016
International audienceIn this work, novel archaeosomes based on Egg-PC and a mixture of PEGylated archaeal tetraether lipids were investigated as nanocarriers for in vitro delivery of an original anticancer peptide.
Jiblaoui, A., Benvegnu, T., Barbeau, J., Glippa, V., Vivès, T., Cormier, P., Cosson, B.   +6 more
core   +1 more source

Phase contrast microscope images of archaeosomes composed of different mixtures of archaeabacterial lipids.

, 2013
Archaeosomes composed of different mixtures of archaebacterial lipids as indicated in individual panels. Panel A shows different regions in the same observation chamber.
Vid Šuštar (316735), Ajda Ota (316739), Angela Corcelli (222554), Veronika Kralj-Iglič (316740), Simona Lobasso (316738), Patrizia Lopalco (316737), Jasna Zelko (316736), Nataša Poklar Ulrih (155068)   +7 more
core   +1 more source

Archaeosomes induce long-term CD8 + cytotoxic response to entrapped soluble protein by the exogenous cytosolic pathway, in the absence of CD4 + T cell help

, 2000
The unique ether glycerolipids of Archaea can be formulated into vesicles (archaeosomes) with strong adjuvant activity for MHC class II presentation.
Sad, Subash, Patel, G., Sprott, G., Krishnan, Lakshmi   +3 more
core   +1 more source

CHARACTERIZATION OF THERMOSENSITIVE HYBRID ARCHAEOSOMES AND DPA-CY3[22,22]/POPC LIPOSOMES AND IN VITRO EVALUATION OF THEIR POTENTIAL USEFULNESS IN TARGETED DELIVERY AND CONTROLLED RELEASE [PDF]

, 2016
One of earlier challenges in treating cancer was utilizing drugs that are powerful yet do not cause severe toxicity to patients. Although the use of liposomal drugs has somewhat met that challenge, our objective now is to create liposomal drugs with an ...
Ayesa, Umme
core   +1 more source

New generation of liposomes called archaeosomes based on natural or synthetic archaeal lipids as innovative formulations for drug delivery.

, 2009
International audienceArchaeosomes made from natural archaeal membrane lipids and/or synthetic lipid analogues have been extensively studied for potential applications in drug and vaccine delivery over the past decade only.
Cammas-Marion, Sandrine, Lemiègre, Loïc, Benvegnu, Thierry   +2 more
core   +1 more source