Results 51 to 60 of about 518 (150)

Illuminating the Petite Picture of T Cell Memory Responses to Listeria monocytogenes

BioMed Research International, Volume 2013, Issue 1, 2013., 2013
The ease to culture, moderately less safety constraints in handling, and above all, hurdle free induction of an anticipated infection in mouse rendered Listeria monocytogenes the rank of a model organism for studying a variety of host immune responses. Listeria monocytogenes being an intracellular pathogen evokes potent CD8 T cell response during which
Saba Tufail, Khan Farheen Badrealam, Mohammad Owais, Swaleha Zubair, Anshu Agrawal   +4 more
wiley   +1 more source

The Potent In Vitro Skin Permeation of Archaeosome Made from Lipids Extracted of Sulfolobus acidocaldarius

Archaea, Volume 2013, Issue 1, 2013., 2013
Archaeosomes are a new generation of liposomes that exhibit higher stabilities under different conditions, such as high temperatures, alkaline or acidic pH, and presence of bile salts in comparison with liposomes, and can be used in biotechnology including drug, gene, and vaccine delivery.
Eskandar Moghimipour, Mohammad Kargar, Zahra Ramezani, Somayeh Handali, Nejat Düzgünes   +4 more
wiley   +1 more source

Archaeosomes: an excellent carrier for drug and cell delivery

Drug Delivery, 2015
Archaeosomes as liposomes made with one or more ether lipids that are unique to the domain of Archaeobacteria, found in Archaea constitute a novel family of liposome. Achaean-type lipids consist of archaeol (diether) and/or caldarchaeol (tetraether) core structures.
Gurmeet, Kaur, Tarun, Garg, Goutam, Rath, Amit K, Goyal   +3 more
openaire   +2 more sources

Physical Properties and Membrane Packing in Hybrid Archaeosomes [PDF]

Biophysical Journal, 2015
In this study, we have characterized the physical properties of liposomes made of archaeal bipolar tetraether lipids (BTL) and “conventional” monopolar diester lipids (termed as hybrid archaeosomes). We used the polar lipid fraction E (PLFE) isolated from the thermoacidophilic archaeon Sulfolobus acidocaldarius as the BTL component of the hybrid ...
Ayesa, Umme, Chong, Parkson L.G.
openaire   +1 more source

Nanoparticle‐Based Drug Delivery for Therapy of Lung Cancer: Progress and Challenges

Journal of Nanomaterials, Volume 2013, Issue 1, 2013., 2013
The last decade has witnessed enormous advances in the development and application of nanotechnology in cancer detection, diagnosis, and therapy culminating in the development of the nascent field of “cancer nanomedicine.” A nanoparticle as per the National Institutes of Health (NIH) guidelines is any material that is used in the formulation of a drug ...
Anish Babu, Amanda K. Templeton, Anupama Munshi, Rajagopal Ramesh, Haifeng Chen   +4 more
wiley   +1 more source

Archaeosomes made of Halorubrum tebenquichense total polar lipids: a new source of adjuvancy

BMC Biotechnology, 2009
Background Archaeosomes (ARC), vesicles prepared from total polar lipids (TPL) extracted from selected genera and species from the Archaea domain, elicit both antibody and cell-mediated immunity to the entrapped antigen, as well as efficient cross ...
Morilla Maria, Corral Ricardo S, Roncaglia Diana I, Morelli Irma, Bilen Marcos, Cutrullis Romina A, Higa Leticia H, Gonzalez Raul O, Petray Patricia B, Romero Eder L   +9 more
doaj   +1 more source

Intranasal administration of unadjuvanted SARS‐CoV‐2 spike antigen boosts antigen‐specific immune responses induced by parenteral protein subunit vaccine prime in mice and hamsters

European Journal of Immunology, Volume 54, Issue 6, June 2024.
Intranasal administration of spike protein antigen alone following an intramuscular prime with spike protein antigen adjuvanted with sulfated lactosylarchaeol (SLA) archaeosomes boosts systemic and mucosal immune responses, leading to protection from SARS‐CoV‐2 infection.
Gerard Agbayani, Bassel Akache, Tyler M. Renner, Anh Tran, Matthew Stuible, Renu Dudani, Blair A. Harrison, Diana Duque, Jegarubee Bavananthasivam, Lise Deschatelets, Usha D. Hemraz, Sophie Régnier, Yves Durocher, Michael J. McCluskie   +13 more
wiley   +1 more source

On Physical Properties of Tetraether Lipid Membranes: Effects of Cyclopentane Rings

Archaea, Volume 2012, Issue 1, 2012., 2012
This paper reviews the recent findings related to the physical properties of tetraether lipid membranes, with special attention to the effects of the number, position, and configuration of cyclopentane rings on membrane properties. We discuss the findings obtained from liposomes and monolayers, composed of naturally occurring archaeal tetraether lipids
Parkson Lee-Gau Chong, Umme Ayesa, Varsha Prakash Daswani, Ellah Chay Hur, Yosuke Koga   +4 more
wiley   +1 more source

Archaeosome: As New Drug Carrier for Delivery of Paclitaxel to Breast Cancer [PDF]

Indian Journal of Clinical Biochemistry, 2013
In the present study, paclitaxel was archaeosomed to reduce side effects and improve its therapeutic index. Carriers have made a big evolution in treatment of many diseases in recent years. Lipid carriers are of special importance among carriers. Archaeosome is one of the lipid carriers.
Alavi, Seyed Ebrahim, Mansouri, Hamidreza, Esfahani, Maedeh Koohi Moftakhari, Movahedi, Fatemeh, Akbarzadeh, Azim, Chiani, Mohsen   +5 more
openaire   +5 more sources

Tetraether archaeal lipids promote long‐term survival in extreme conditions

Molecular Microbiology, Volume 121, Issue 5, Page 882-894, May 2024.
Unique archaeal lipid membrane composition, including membrane‐spanning, tetraether lipids, presumably contribute to survival in extreme pH, temperature, and salinity. The biosynthesis of tetraether lipids in the model species Thermococcus kodakarensis promotes survival at high temperatures, and we demonstrate that alternative lipid species are ...
Geraldy Lie Stefanus Liman, Andy A. Garcia, Kristin A. Fluke, Hayden R. Anderson, Sarah C. Davidson, Paula V. Welander, Thomas J. Santangelo   +6 more
wiley   +1 more source