Results 41 to 50 of about 134,557 (313)

Measuring physical disorder of architectural façades for informing better urban renewal using deep learning and space syntax

open access: yesFrontiers in Sustainable Cities
With the emergence of human-centered urban development goals and the increasing pursuit of a better quality of life, the architectural façades of cities are receiving growing attention.
Huiyue Xing, Haojun Shi, Yufan Sun
doaj   +1 more source

Analysing how constraints impact architectural decision-making [PDF]

open access: yes, 2015
Architectural design projects are characterised by a high number of constraints. Along with planning, energy performance and fire safety regulations, current designers have to face constraining factors related to budget, acoustics, orientation, wind ...
De Meyer, Ronald   +2 more
core   +1 more source

Conversation and critique within the architectural design process: a linkograph analysis [PDF]

open access: yes, 2014
Conversation and critique are central to architectural design practice as they function as tools for probing and further improving design ideas.
De Meyer, Ronald   +3 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Energy and technological refurbishment of the School of Architecture Valle Giulia, Rome [PDF]

open access: yes, 2017
Modern architecture built in historical urban contexts represents a demanding issue when its energy efficiency should be improved. Indeed, the strongest efforts have to be made to maintain the architectural identity and its harmony with the surrounding ...
Clemente, C.   +3 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

International tourism in Małopolskie Województwo: the present situation and prospects for development [PDF]

open access: yes, 2009
Małopolskie Województwo is one of the most popular tourist regions in Poland. Due to many attractions, long traditions of hosting tourists and well-developed accommodation facilities, Małopolskie Województwo has become the destination for a growing ...
Kurek, Włodzimierz   +1 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Ancient Cartographies as a Basis for Geolocation Models in Public Space: The Case of Giambattista Nolli and its Heritage Application [PDF]

open access: yes, 2019
In 1748, the architect and surveyor Giambattista Nolli mapped an abstract reality of the city of Rome. As a challenge to the inherited projections, it represented the city mixing streets, halls, corridors, churches, baths and markets as part of a unique ...
Cubero Hernández, Antonio   +2 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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