Results 51 to 60 of about 182,286 (288)

Analysis of Software Binaries for Reengineering-Driven Product Line Architecture\^aAn Industrial Case Study

open access: yes, 2015
This paper describes a method for the recovering of software architectures from a set of similar (but unrelated) software products in binary form. One intention is to drive refactoring into software product lines and combine architecture recovery with ...
Blech, Jan Olaf   +5 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Architectural survey and documentation for the conservation of historic urban centre. The case study of L’Aquila after the earthquake of 2009.

open access: yesDisegnare con, 2012
The Seminar is part of the activities of the Research of National Interest MIUR PRIN 2008 financed by Italian Ministry for Education University and Research, titled “Complex models for architectural and urban heritage”,  with the participation  of five ...
Mario Centofanti
doaj   +1 more source

Teaching, research and practice - establishing a productive balance (Raising the game) [PDF]

open access: yes, 2002
The current debates on teaching standards, on research assessment and on the condition of the profession tend to be carried on in isolation from each other.
Murray, G.
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

L’innovazione nel rilievo fotografico per la conoscenza, la documentazione e la fruizione dei beni culturali

open access: yesDisegnare con, 2013
Sin dagli albori della sua invenzione, la fotografia ha giocato un ruolo essenziale nella rappresentazione dell’architettura. Caratteristica del nostro tempo, essa ha permesso una nuova visione sul mondo e la definizione di un nuovo linguaggio che ha ...
Alessio Cardaci, Antonella Versaci
doaj   +1 more source

Analysing how constraints impact architectural decision-making [PDF]

open access: yes, 2015
Architectural design projects are characterised by a high number of constraints. Along with planning, energy performance and fire safety regulations, current designers have to face constraining factors related to budget, acoustics, orientation, wind ...
De Meyer, Ronald   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Geospatial Analysis for Decoding Architectural Configuration of Ruins of a Coastal Fort: The Case of Fort Vijaydurg, Konkan, India [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Documentation and architectural interpretation of ruins of historic buildings is a complex process. Architectural interpretation based on inadequate documentation can result in an undervalued understanding of historic significance and, consequently ...
M. Mane, D. Nakrani
doaj   +1 more source

Recording, Documentation, and Information Management for the Conservation of Heritage Places: Guiding Principles [PDF]

open access: yes, 2008
Provides guidance on integrating recording, documentation, and information management of territories, sites, groups of buildings, or monuments into the conservation process; evaluating proposals; consulting specialists; and controlling ...
Francois LeBlanc   +2 more
core  

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