Results 51 to 60 of about 6,326,613 (348)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

An Architecture for Differentiated Services

Request for Comments, 1998
This document defines an architecture for implementing scalable service differentiation in the Internet. This architecture achieves scalability by aggregating traffic classification state which is conveyed by means of IP-layer packet marking using the DS
S. Blake, D. Black, M. Carlson, Elwyn B. Davies, Zhirui Wang, W. Weiss   +5 more
semanticscholar   +1 more source

„Ptačí kůstka dutá“ – role Zbyňka Žáby při archeologickém výzkumu Ptahšepsesovy mastaby // “Avian hollow bonelet” – The role of Zbyněk Žába during the archaeological excavation in the mastaba of Ptahshepses [PDF]

Pražské Egyptologické Studie, 2017
Professor Zbyněk Žába laid, through his scholarly and organizational activities at the end of the 1950s and during the 1960s, the foundations for today’s success of the Czech Egyptology.
Jaromír Krejčí
doaj  

Electroencephalographic correlates of sensorimotor integration and embodiment during the appreciation of virtual architectural environments

Frontiers in Psychology, 2015
Nowadays there is the hope that neuroscientific findings will contribute to the improvement of building design in order to create environments which satisfy man’s demands. This can be achieved through the understanding of neurophysiological correlates of
Giovanni eVecchiato, Gaetano eTieri, Gaetano eTieri, Andrea eJelic, Federico eDe Matteis, Anton Giulio Maglione, Fabio eBabiloni   +6 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

QAA subject benchmark statement architecture : version for consultation December 2019 [PDF]

, 2019
The Statement is intended to guide lecturers and course leaders in the design of academic courses leading to qualifications in architecture, it will also be useful to those developing other related courses.
Garstecki, P, Gloster, D, Marshall, O, Matthews, E, McClean, D, Roberts, A, Vowles, H, Vowles, H, Walker, PA, Wright, A   +9 more
core   +1 more source

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

FEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez, Cristina Velez‐delValle, Claudia Patricia Hernández‐Mosqueira, Walid Kuri‐Harcuch   +3 more
wiley   +1 more source

Digital Light Processing of 2D Lattice Composites for Tunable Self‐Sensing and Mechanical Performance

Advanced Engineering Materials, EarlyView., 2023
The study presents the mechanical and in situ sensing performance of digital light processing‐enabled 2D lattice nanocomposites under monotonic tensile and repeated cyclic loading, and provides guidelines for the design of architectures suitable for strain sensors and smart lightweight structures.
Omar Waqas Saadi, Mohammed Ayaz Uddin, Andreas Schiffer, Shanmugam Kumar   +3 more
wiley   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion

Advanced Engineering Materials, EarlyView., 2023
Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal, Yong Pang, Ian Maskery, Ian Ashcroft, Wei Sun, Tao Liu   +5 more
wiley   +1 more source