Results 61 to 70 of about 4,689,971 (325)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

crises

open access: yesПроект Байкал, 2023
One British publishing company has chosen ‘permacrisis’ as the word of the year for 2022. In fact, the crisis has been permanent for the time longer than one year. Over the last few decades, crises have become so integrated into our lives that they look
Елена Григорьева
doaj   +1 more source

Philosophy & Architecture [PDF]

open access: yes, 2016
Philosophy & Architecture special number of philosophy@LISBON (International eJournal) 5 | 2016 edited by Tomás N. Castro with Maribel Mendes Sobreira Centro de Filosofia da Universidade de Lisboa
Castro, Tomás N.   +1 more
core  

MORA - an architecture and programming model for a resource efficient coarse grained reconfigurable processor [PDF]

open access: yes, 2009
This paper presents an architecture and implementation details for MORA, a novel coarse grained reconfigurable processor for accelerating media processing applications. The MORA architecture involves a 2-D array of several such processors, to deliver low
Chalamalasetti, S.R.   +3 more
core   +1 more source

Instant architecture

open access: yesACM Transactions on Graphics, 2003
This paper presents a new method for the automatic modeling of architecture. Building designs are derived using split grammars, a new type of parametric set grammar based on the concept of shape. The paper also introduces an attribute matching system and a separate control grammar, which offer the flexibility required to model buildings using a large ...
Wonka, Peter   +3 more
openaire   +3 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Low Power Shift and Add Multiplier Design [PDF]

open access: yes, 2010
Today every circuit has to face the power consumption issue for both portable device aiming at large battery life and high end circuits avoiding cooling packages and reliability issues that are too complex.
Marimuthu, C. N.   +2 more
core   +2 more sources

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Laminar Cortical Architecture [PDF]

open access: yes, 2000
Defense Advanced Research Projects Agency and the Office of Naval Research (NOOOI4-95-I-0409); National Science Foundation (IRI-97-20333); Office of Naval Research (NOOOI4-95-I-0657)
Grossberg, Stephen
core   +1 more source

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

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