Results 71 to 80 of about 6,719,355 (312)
Actin bundle architecture and mechanics regulate myosin II force generation [PDF]
, 2021 Kimberly L. Weirich +3 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The Structure of Space and Problems of Our Time
Проект БайкалSince antiquity the image of space as emptiness has been opposed to the image of material space filled with some essence. For a long time this role was played by the theories of ether.
Светлана Головня +1 more
doaj +1 more source
The Mysteries of Rural Architecture [PDF]
مسکن و محیط روستا, 2010 The rural architecture is all about house it starts with a house and yet it ends with a house. The rural house is quite simple and calm, but in the meanwhile it enjoys some complexity in the sense of wisdom.
doaj
Dissecting shared genetic architecture between obesity and multiple sclerosis [PDF]
, 2023 Ruijie Zeng +12 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Intelligent Models and Architectures for Global Learning-Oriented Cooperation
IEEE AccessThis paper presents the design of intelligent models and architectures for global learning-oriented cooperation. The research work brings our current investigations towards the definition of a general development methodology for global intelligent ...
Ana M. Gonzalez de Miguel +1 more
doaj +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Reproductive resilience but not root architecture underpins yield improvement under drought in maize [PDF]
, 2021 Carlos D. Messina +10 more
openalex +1 more source
Molecular Oncology, EarlyView.Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser +11 more
wiley +1 more source