Results 81 to 90 of about 1,565,190 (299)

Everyone’s Going to be an Architect: Design Principles for Architectural Thinking in Agile Organizations [PDF]

, 2020
Bettina Horlach, Andreas Drechsler, Ingrid Schirmer, Paul Drews   +3 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A Deep Learning Architecture for Temporal Sleep Stage Classification Using Multivariate and Multimodal Time Series [PDF]

, 2018
Stanislas Chambon, Mathieu Galtier, Pierrick J. Arnal, Gilles Wainrib, Alexandre Gramfort   +4 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Bajo el signo de la esvástica. La Exposición de Arquitectura Moderna alemana en España (1942)

Diacronie. Studi di Storia Contemporanea, 2014
In autumn of 1942, Barcelona received the Exhibition of Modern German Architecture, directed by Albert Speer. The objective of this exhibition was to show to European allies the pharaonic projects of Germany, the Europa’s future new capital, the new ...
Francesc Vilanova i Vila-Abadal es Profesor Titular de Historia Contemporánea en la Universidad Autónoma de Barcelona y Director del Archivo Carles Pi i Sunyer (Fundació Carles Pi i Sunyer d’Estudis Autonòmics i Locals, Barcelon). Miembro del Grup de Recerca en l’Època Franquista (GREF) y del Centre d’Estudis sobre les Èpoques Franquista i Democràtica (UAB-CEFID).
doaj  

BIOMIMICRY ARCHITECTURE, FROM THE INSPIRATION BY NATURE TO THE INNOVATION OF THE SAHARAN ARCHITECTURE

Architecture and Engineering, 2018
Biomimicry is an old approach, but in the scientific conceptualization is new, as an approach of innovation based on the emulation of Nature, in recent years, this approach brings many potential theories and innovations in the architecture field. Indeed,
Yassine Mohammed Benyoucef, Andrey Razin
doaj   +1 more source

Quantum repeater architecture with hierarchically optimized memory buffer times [PDF]

, 2019
Siddhartha Santra, Liang Jiang, Vladimir S Malinovsky   +2 more
openalex   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Cultural landscape in theory. 1st Part: Centre, core and triangle [PDF]

Urbani Izziv, 2002
The article presents ideas about the close links between architectural forms in theory and practice, as well as the extraordinary ties between the aspects of various disciplines and architectural expression.
Borut Juvanec
doaj