Results 61 to 70 of about 11,057,218 (281)

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

Notes from the Anti-Displacement Studio

Radical Teacher
This article addresses the question of how design pedagogy and methods can be reformulated and retooled to support community-led anti-displacement planning and design initiatives.
Lily Song
doaj   +1 more source

Transformation of Architectural Design-Research Pedagogy

Architectural Research in Finland
This paper addresses the concept of transformation as a restorative practice with great potential in architectural education. The concept was used as the foundation of a post-professional, research-oriented master’s degree design studio held for the first time during the spring semester of 2022 as a collaboration between two European universities ...
Rosana Rubio Hernández, Guiomar Martín Domínguez, Fernando Nieto Fernández   +2 more
openaire   +4 more sources

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

Advanced Science, EarlyView.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg, Thijs J. van der Burg, Stijn Y. Kolkman, Santiago Saavedra Castano, David Fernandez Rivas, Anke Klingner, Roger M. L. M. Lomme, Lucas S. Joziasse, Dorothee Wasserberg, H. Remco Liefers, Doron Ben Ami, Udi Sadeh, Oded Shoseyov, Giulio Dagnino, Pascal Jonkheijm, Jurgen J. Fütterer, Stefano Stramigioli, J. Frank W. Nijsen, Michiel C. Warlé, Islam S. M. Khalil   +19 more
wiley   +1 more source

Corps enquêteurs et lieux performés

Ambiances, 2018
Teaching the sensory experience of architecture is a necessity as the means of design features become increasingly immaterial. For this reason, a method based on a principle of active pedagogy is proposed, where the student learns by acting, based on ...
Valérie Lebois, Dominique Laburte
doaj   +1 more source

SYNERGISTIC MODEL FOR SUSTAINABLE ENVIRONMENTAL DESIGN PEDAGOGY IN ARCHITECTURAL EDUCATION IN INDIA

Bulletin of South Ural State University series "Construction Engineering and Architecture", 2016
Рави Вэйш, магистр архитектуры, доцент и научный сотрудник, кафедра архитектуры, университет науки и технологий Динбандху Чхоту Рам, Мертал, Сонипат, Харьяна (Индия), rv_an@yahoo.co.in Рави Вэйш, rv_an@yahoo.co.in Университет науки и технологий Динбандху Чхоту Рам, Мертал, Сонипат, Харьяна (Индия)
openaire   +4 more sources

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

Advanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou, Caixi Yu, Guilan Xu, Lijuan Liu, Yujia Liang, Yulin Liang, He Ding, Litu Zhang, Piaoping Yang, Chen Wang   +9 more
wiley   +1 more source

Studio Culture as Competency

Ardeth, 2022
The teaching of design, the act of design itself, and its competencies are always conceived as a mystery – knowable to a certain extent yet unknowable in its totality.
Lilian Chee, Yi-Ern Samuel Tan
doaj  

Computationally Evidence‐Grounded Sequence‐First Design of Peptide Binders

Advanced Science, EarlyView.
BOND‐PEP enables controllable, sequence‐first peptide binder design by grounding generation in binding evidence retrieved for each target. It uses topology‐conditioned message passing to integrate relevant peptide examples with the target protein sequence, forming a residue‐level representation that guides the generation of diverse, target‐specific ...
Wenze Ding
wiley   +1 more source

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

Advanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo, Qianqian Zhang, Chenhao Wang, Zhiheng Yi, Alex Jinpeng Wang, Jing Tang, Min Li   +6 more
wiley   +1 more source