Results 101 to 110 of about 372,803 (361)
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Лëд и снег, 2015 In November 2010 a new research unit was inaugurated in Arctic and Antarctic Research Institute (St. Petersburg) – Climate and Environmental Research Laboratory (CERL) – that became the first lab in Russia dedicated to the complex studies of ice cores ...
V. Ya. Lipenkov +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Inoculation of seed with strains of nitrogen-fixing bacteria (exampled by oats and millet) [PDF]
BIO Web of ConferencesAs a result of the conducted researches the expediency and effectiveness of pre-sowing inoculation of seeds of field crops with strains of nitrogen-fixing bacteria has been proved, which allows to increase fodder productivity of oat and pearl millet ...
Osipova Valentina +7 more
doaj +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
Understanding Arctic Ocean Circulation: A Review of Ocean Dynamics in a Changing Climate
, 2020 12 The Arctic Ocean is a focal point of climate change, with ocean warming, freshening, 13 sea-ice decline and circulation that link to the changing atmospheric and terrestrial en14 vironment. Major features of the Arctic and the interconnected nature of
M. Timmermans, J. Marshall
semanticscholar +1 more source
Nature, 1875 THE absence of sunlight during the Arctic winter is said to have an injurious effect on the health of both men and dogs; yet it does not appear that the best substitute for solar light has ever been employed for illuminating purposes during the dark season.
openaire +3 more sources
Molecular Oncology, EarlyView.Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun +5 more
wiley +1 more source
Nature, 1876 Two or three considerations have led me to believe that possibly the recent Arctic Expedition has not been so fortunate as might have been wished, and that the same amount of foresight, courage, and energy, expended on a similar expedition another year might be attended with much more satisfactory results.
openaire +2 more sources
Earthing effects on mitochondrial function: ATP production and ROS generation
FEBS Open Bio, EarlyView.In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley +1 more source