Results 111 to 120 of about 582,222 (384)

Emergency department physicians’ experiences and perceptions with medication-related work tasks and the potential role of clinical pharmacists

International Journal of Qualitative Studies on Health & Well-Being, 2023
Purpose Medication-related problems are frequent among emergency department patients. Clinical pharmacists play an important role in identifying, solving, and preventing these problems, but are not present in emergency departments worldwide.
Tine Johnsgård, Renate Elenjord, Elin C. Lehnbom, Torsten Risør, Birgitte Zahl-Holmstad, Renata Vesela Holis, Eirik Hugaas Ofstad, Beate Hennie Garcia   +7 more
doaj   +1 more source

Arctic–CHAMP: A program to study Arctic hydrology and its role in global change [PDF]

, 2002
The Arctic constitutes a unique and important environment that is central to the dynamics and evolution of the Earth system. The Arctic water cycle, which controls countless physical, chemical, and biotic processes, is also unique and important.
Bromwhich, David, Hamilton, Lawrence C., Hinzman, Larry, Morison, James, Peterson, Bruce, Romanovsky, Vladimir, Sturm, Matthew, Vorosmarty, Charles J., Webb, Robert   +8 more
core   +4 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Probability Assessments of an Ice-Free Arctic: Comparing Statistical and Climate Model Projections [PDF]

arXiv, 2019
The downward trend in the amount of Arctic sea ice has a wide range of environmental and economic consequences including important effects on the pace and intensity of global climate change. Based on several decades of satellite data, we provide statistical forecasts of Arctic sea ice extent during the rest of this century. The best fitting statistical
arxiv  

Optimal Combination of Arctic Sea Ice Extent Measures: A Dynamic Factor Modeling Approach [PDF]

arXiv, 2020
The diminishing extent of Arctic sea ice is a key indicator of climate change as well as an accelerant for future global warming. Since 1978, Arctic sea ice has been measured using satellite-based microwave sensing; however, different measures of Arctic sea ice extent have been made available based on differing algorithmic transformations of the raw ...
arxiv  

Hypsometry and Volume of the Arctic Ocean and Its Constituent Seas [PDF]

, 2002
This paper presents an analysis of the Arctic Ocean and its constituent seas for seafloor area distribution versus depth and ocean volume. The bathymetry from the International Bathymetric Chart of the Arctic Ocean (IBCAO) is used together with limits ...
Aagard, Bischof, Brozovic, Dawes, Dyke, Elverhøi, Fairbanks, Grosswald, Guilderson, Head Department of Navigation and Oceanography (HDNO), Jakobsson, Jakobsson, Kleiber, Mangerud, Martin Jakobsson, Menard, Nørgaard-Pedersen, Pusharovsky, Rudels, Smith, Soluri, Svendsen, Wessel   +22 more
core   +2 more sources

Germline variants in CDKN2A wild‐type melanoma prone families

Molecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen, Marie Loeng, Amalie Lund Holth, Per E. Lønning, Jürgen Geisler, Stian Knappskog   +5 more
wiley   +1 more source

Arctic Sea Ice State Estimation From Thermodynamic PDE Model [PDF]

arXiv, 2019
Recent rapid loss of the Arctic sea ice motivates the study of the Arctic sea ice thickness. Global climate model that describes the ice's thickness evolution requires an accurate spatial temperature profile of the Arctic sea ice. However, measuring the complete temperature profile is not feasible within and throughout the Arctic icecap.
arxiv  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Development of a methodology for automated processing of spatial data of agricultural land based on machine learning [PDF]

E3S Web of Conferences
Agriculture industry in Russia is an important part of the economy. Therefore, this industry must be highly efficient and profitable. The usage of remote sensing data for field monitoring makes it possible to simplify the process of collecting ...
Berezovsky Vladimir, Aleshko Roman, Shoshina Ksenia, Vasendina Irina   +3 more
doaj   +1 more source