Results 71 to 80 of about 37,305 (333)
Scientific Reports, 2023 As a result of global warming, the area of the polar pack ice is diminishing, making merchant travel more practical. Even if Arctic ice thickness reduced in the summer, fractured ice is still presenting operational risks to the future navigation.
Oleg Gaidai +5 more
doaj +1 more source
2017 State-of the Science of Dispersants and Dispersed Oil (DDO) in U.S. Arctic Waters: Physical Transport and Chemical Behavior [PDF]
, 2017 Chemical dispersants were employed on an unprecedented scale during the Deepwater Horizon oil spill in the Gulf of Mexico, and could be a response option should a large spill occur in Arctic waters. The use of dispersants in response to that spill raised
Coastal Response Research Center (CRRC)
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Automatic detection of Arctic polynyas using hybrid supervised-unsupervised deep learning [PDF]
The CryospherePolynyas are open water or thin-ice areas within the ice pack. They play a crucial role for the Earth system, from deep water to cloud formation, causing large gas exchanges, and acting as hotspots for marine life.
C. Heuzé, C. H. M. Wong
doaj +1 more source
Concentrations and snow-atmosphere fluxes of reactive nitrogen at Summit, Greenland [PDF]
, 1999 Concentrations and fluxes of NOy (total reactive nitrogen), ozone concentrations and fluxes of sensible heat, water vapor, and momentum were measured from May 1 to July 20, 1995 at Summit, Greenland. Median NOy concentrations declined from 947 ppt in May
Colman, A S +4 more
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
CLIMATE CHANGE AT HIGH LATITUDES: AN ILLUMINATING EXAMPLE
Zygon, 2018 A striking example is presented of a newly observed phenomenon in the ice‐covered Arctic Ocean that appears to be a consequence of changes in the physical forcing.
doaj +2 more sources
Environmental drivers of under-ice phytoplankton bloom dynamics in the Arctic Ocean
Elementa: Science of the Anthropocene, 2020 The decline of sea-ice thickness, area, and volume due to the transition from multi-year to first-year sea ice has improved the under-ice light environment for pelagic Arctic ecosystems.
Mathieu Ardyna +17 more
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Sudden increase in Antarctic sea ice: Fact or artifact? [PDF]
, 2013 Copyright © 2011 American Geophysical UnionThree sea ice data sets commonly used for climate research display a large and abrupt increase in Antarctic sea ice area (SIA) in recent years.
Cavalieri +16 more
core +1 more source