Results 161 to 170 of about 161,658 (309)

Enhanced Arctic sea ice melting controlled by larger heat discharge of mid-Holocene rivers. [PDF]

Nat Commun, 2022
Dong J, Shi X, Gong X, Astakhov AS, Hu L, Liu X, Yang G, Wang Y, Vasilenko Y, Qiao S, Bosin A, Lohmann G.   +11 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Bathymetry-constrained ocean geostrophic currents play a key role in shaping the sea ice circulation in the Canada Basin, Arctic Ocean

Environmental Research Letters
Satellite-based observations and a pan-Arctic coupled sea ice-ocean model are utilized to study the effect of ocean geostrophic currents on large-scale sea ice circulation in the Canada Basin, Arctic Ocean.
Hengling Leng, Hailun He, Dake Chen, Peigen Lin, Yang Yang, Zhaomin Wang   +5 more
doaj   +1 more source

Heavy footprints of upper-ocean eddies on weakened Arctic sea ice in marginal ice zones. [PDF]

Nat Commun, 2022
Manucharyan GE, Thompson AF.
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Assessment of Hydrocarbon Degradation Potential in Microbial Communities in Arctic Sea Ice. [PDF]

Microorganisms, 2022
Peeb A, Dang NP, Truu M, Nõlvak H, Petrich C, Truu J.   +5 more
europepmc   +1 more source

Ice in Arctic Seas [PDF]

Nature, 1932
openaire   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Seasonal Arctic sea ice forecasting with probabilistic deep learning. [PDF]

Nat Commun, 2021
Andersson TR, Hosking JS, Pérez-Ortiz M, Paige B, Elliott A, Russell C, Law S, Jones DC, Wilkinson J, Phillips T, Byrne J, Tietsche S, Sarojini BB, Blanchard-Wrigglesworth E, Aksenov Y, Downie R, Shuckburgh E.   +16 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source