Results 51 to 60 of about 161,658 (309)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disentangling the Coupled Atmosphere‐Ocean‐Ice Interactions Driving Arctic Sea Ice Response to CO2 Increases

open access: yesJournal of Advances in Modeling Earth Systems, 2020
A novel decomposition of the ocean heat energy that contributes to sea ice melt and growth (ocean‐ice and frazil heat) into components that are driven by surface heat flux and ocean circulation changes is used to isolate the evolving roles of the ...
Oluwayemi A. Garuba   +3 more
doaj   +1 more source

Underrepresentation of the Linkage between the Barents–Kara Sea Ice and East Asian Rainfall in Early Summer by CMIP6 Models

open access: yesAtmosphere, 2023
Our previous study revealed the link between Barents–Kara sea ice and rainfall in eastern China. This study continues evaluating the performance of multiple models from phase 6 of the Coupled Model Intercomparison Project (CMIP6) in simulating this ...
Haohan Chen   +4 more
doaj   +1 more source

Nonlinear threshold behavior during the loss of Arctic sea ice [PDF]

open access: yes, 2009
In light of the rapid recent retreat of Arctic sea ice, a number of studies have discussed the possibility of a critical threshold (or “tipping point”) beyond which the ice–albedo feedback causes the ice cover to melt away in an irreversible process. The
Eisenman, I., Wettlaufer, J. S.
core   +3 more sources

Prediction of monthly Arctic sea ice concentrations using satellite and reanalysis data based on convolutional neural networks [PDF]

open access: yes, 2020
Changes in Arctic sea ice affect atmospheric circulation, ocean current, and polar ecosystems. There have been unprecedented decreases in the amount of Arctic sea ice due to global warming.
Han, Daehyeon   +4 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Arctic Ice Ocean Prediction System: evaluating sea-ice forecasts during Xuelong's first trans-Arctic Passage in summer 2017

open access: yesJournal of Glaciology, 2019
In an effort to improve the reliability of Arctic sea-ice predictions, an ensemble-based Arctic Ice Ocean Prediction System (ArcIOPS) has been developed to meet operational demands.
Longjiang Mu   +4 more
doaj   +1 more source

Biomarker Distributions in (Sub)‐Arctic Surface Sediments and Their Potential for Sea Ice Reconstructions

open access: yesGeochemistry, Geophysics, Geosystems, 2020
To evaluate the present sea ice changes in a longer‐term perspective, the knowledge of sea ice variability on preindustrial and geological time scales is essential.
Henriette M. Kolling   +5 more
doaj   +1 more source

The reversibility of sea ice loss in a state-of-the-art climate model [PDF]

open access: yes, 2011
Rapid Arctic sea ice retreat has fueled speculation about the possibility of threshold (or ‘tipping point’) behavior and irreversible loss of the sea ice cover. We test sea ice reversibility within a state-of-the-art atmosphere–ocean global climate model
Armour, K. C.   +4 more
core  

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