Results 111 to 120 of about 333,091 (340)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

INARI DECLARATION 2002 on the occasion of the Third Ministerial Meeting of THE ARCTIC COUNCIL [PDF]

, 2002
INARI DECLARATION on the occasion of the Third Ministerial Meeting of THE ARCTIC COUNCIL, October ...
Arctic Council, -
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Formation of the Atlantic Meridional Overturning Circulation lower limb is critically dependent on Atlantic-Arctic mixing

Nature Communications
Deep-water formation in the eastern Subpolar North Atlantic Ocean (eSPNA) and Nordic Seas is crucial for maintaining the lower limb of the Atlantic Meridional Overturning Circulation (AMOC), of consequence for global climate.
Dipanjan Dey, Robert Marsh, Sybren Drijfhout, Simon A. Josey, Bablu Sinha, Jeremy Grist, Kristofer Döös   +6 more
doaj   +1 more source

The Inuvik Declaration, 1996. Declaration from the Ministerial meeting of the Arctic Environmental Protection Strategy (AEPS)held in Inuvik, Canada. [PDF]

, 1996
The Inuvik Declaration, March 21,1996. Declaration from the Ministerial meeting of the Arctic Environmental Protection Strategy (AEPS)held in Inuvik, Canada.
Arctic Council, -
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

BARROW DECLARATION 2000 on the occasion of the Second Ministerial Meeting of THE ARCTIC COUNCIL [PDF]

, 2000
BARROW DECLARATION on the occasion of the Second Ministerial Meeting of THE ARCTIC COUNCIL, October ...
Arctic Council, -
core   +1 more source

Warming in the Nordic Seas, North Atlantic storms and thinning Arctic sea ice

Environmental Research Letters, 2017
Arctic sea ice over the last few decades has experienced a significant decline in coverage both in summer and winter. The currently warming Atlantic Water layer has a pronounced impact on sea ice in the Nordic Seas (including the Barents Sea).
Vladimir A Alexeev, John E Walsh, Vladimir V Ivanov, Vladimir A Semenov, Alexander V Smirnov   +4 more
doaj   +1 more source

Arctic intermediate water in the Norwegian sea [PDF]

Deep Sea Research Part A. Oceanographic Research Papers, 1990
Abstract At least two types of intermediate water propagate into the Norwegian Sea from the Iceland and Greenland seas. North Icelandic Winter Water flows along the slope of the Faroe-Iceland Ridge towards the Faroes. The distribution of this intermediate water is limited to the southern Norwegian Sea.
openaire   +2 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source