Results 91 to 100 of about 333,091 (340)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

Drivers of Changing Interannual Variability in Autumn‐Early Winter Arctic Sea Ice (1950–2024)

open access: yesGeophysical Research Letters
Arctic sea ice has undergone a pronounced decline over recent decades, yet the drivers of its interannual variability remains unclear. Here we utilize standard deviation to assess long‐term changes in autumn‐early winter (October–December) Arctic sea ice
Lejiang Yu, Shiyuan Zhong, Timo Vihma
doaj   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

The Toll of the Arctic Seas

open access: yesBulletin of the American Geographical Society, 1911
References: p. 435-437. ; Mode of access: Internet.
openaire   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Data of polycyclic aromatic hydrocarbons concentration in the Siberian Arctic seas sediments. [PDF]

open access: yesData Brief, 2022
Lakhmanov DE   +4 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Arctic Environmental Protection Strategy (AEPS) Ministerial Meeting in Alta, Norway. 1997 [PDF]

open access: yes, 1997
Arctic Environmental Protection Strategy (AEPS) is the predecessor of the Arctic Council, established in Rovaniemi Finland in 1991.
Arctic Council, -
core   +1 more source

Radiogenic isotope (Nd, Pb, Sr) signatures of surface and sea ice-transported sediments from the Arctic Ocean under the present interglacial conditions

open access: yesPolar Research, 2018
Under modern conditions, sediments from the large continental shelves of the Arctic Ocean are mixed by currents, incorporated into sea ice and redistributed over the Arctic Basin through the Beaufort Gyre and Trans-Polar Drift major sea-ice routes. Here,
Jenny Maccali   +2 more
doaj   +1 more source

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