Results 91 to 100 of about 306,735 (293)

Export of nutrients from the Arctic Ocean [PDF]

, 2013
This study provides the first physically based mass-balanced transport estimates of dissolved inorganic nutrients (nitrate, phosphate, and silicate) for the Arctic Ocean.
Tsubouchi, T., Whitledge, T.E., Azetsu-Scott, K., Naveira-Garabato, A.C., Petrie, Brian, Torres-valdes, Sinhué, Sanders, Richard, McLaughlin, Fiona A., Azetsu-Scott, Kumiko, Whitledge, Terry E., Sanders, Richards, Sanders, R., Tsubouchi, Takamasa, Kattner, Gerhard, Torres-Valdes, S., McLaughlin, F. A., Bacon, Sheldon, Naveira-Garabato, Alberto C., Petrie, B., Bacon, S.   +19 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Agreement on Cooperation on Aeronautical and Maritime Search and Rescue in the Arctic [PDF]

, 2011
Agreement on Cooperation on Aeronautical and Maritime Search and Rescue in the Arctic - The SAR Agreement is the first legally binding agreement established under the auspices of the Arctic Council.
Arctic Council, -
core   +1 more source

Optimizing sea ice parameters mitigates the underestimation of Arctic marine access in CMIP6 climate models

Communications Earth & Environment
Maritime activity in the Arctic is increasing, and climate change projections suggest that commercial vessels may soon have seasonal access to high-latitude waters.
Chao Min, Qinghua Yang, Hao Luo, Frank Kauker, Qi Shu, Xin Wang, Jiping Liu, Dake Chen   +7 more
doaj   +1 more source

Arctic Offshore Oil in Russia: Optimism, Pessimism and Realism

Контуры глобальных трансформаций: политика, экономика, право, 2021
A strong global interest in the hydrocarbon resources of the Arctic emerged in the mid-2000s, after the US Geological Survey published data on its petroleum potential.
N. N. Poussenkova
doaj  

Arctic intermediate water in the Norwegian sea [PDF]

Deep Sea Research Part A. Oceanographic Research Papers, 1990
Abstract At least two types of intermediate water propagate into the Norwegian Sea from the Iceland and Greenland seas. North Icelandic Winter Water flows along the slope of the Faroe-Iceland Ridge towards the Faroes. The distribution of this intermediate water is limited to the southern Norwegian Sea.
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

The Inuvik Declaration, 1996. Declaration from the Ministerial meeting of the Arctic Environmental Protection Strategy (AEPS)held in Inuvik, Canada. [PDF]

, 1996
The Inuvik Declaration, March 21,1996. Declaration from the Ministerial meeting of the Arctic Environmental Protection Strategy (AEPS)held in Inuvik, Canada.
Arctic Council, -
core   +1 more source

Formation of the Atlantic Meridional Overturning Circulation lower limb is critically dependent on Atlantic-Arctic mixing

Nature Communications
Deep-water formation in the eastern Subpolar North Atlantic Ocean (eSPNA) and Nordic Seas is crucial for maintaining the lower limb of the Atlantic Meridional Overturning Circulation (AMOC), of consequence for global climate.
Dipanjan Dey, Robert Marsh, Sybren Drijfhout, Simon A. Josey, Bablu Sinha, Jeremy Grist, Kristofer Döös   +6 more
doaj   +1 more source