Arctigenin is a natural plant lignan previously shown to induce G 2/M arrest in SW480 human colon cancer cells as well as AGS human gastric cancer cells, suggesting its use as a possible cancer chemopreventive agent.
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Upregulation of protein kinase B (PKB, also known as Akt) is observed within the cerebral arteries of subarachnoid hemorrhage (SAH) animals. This study is of interest to examine Arctigenin, a potent antioxidant, on endothelial nitric oxide synthase (eNOS)
Chia-Mao Chang +4 more
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Synthetic studies of lignanes: Attempted synthesis of arctigenin and enterolactone
A synthetic approach to bioactive lignans was devised, which relies on photocatalyzed [2+2] cycloaddition of cinnamyl cinnamates, followed by catalytic hydrogenolysis of C-C bond between two benzylic positions in the strained cycloadduct.
Milena Trmcic +3 more
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Saussurea heteromalla (D. Don) Hand.-Mazz.: A new source of arctiin, arctigenin and chlorojanerin
624-626Saussurea heteromalla (D. Don) Hand.-Mazz. (Asteraceae), a Himalayan herb, has been investigated phytochemically for the first time in detail and the plant is being reported here as a new source of two lignans, i.e.
Mishra, Prabhu Dutt +3 more
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A Natural product-based composite nanozyme synergistically induces ferroptosis for lung cancer therapy. [PDF]
Jin Y +10 more
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Integrated Network Pharmacology, Molecular Docking, and Analysis of Active Constituents of Symplocos sumuntia Along With Their Antioxidative Activity. [PDF]
Huong TT +8 more
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Combined Pharmacologic and Nutritional Modulation of High-Fat Diet-Associated Tumor-Supportive Features in Prostate Cancer Models. [PDF]
Wu K +7 more
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The inhibition of pathological IgE in allergic diseases by natural compounds. [PDF]
Carnazza M +6 more
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Retraction: Arctigenin inhibits the progression of colorectal cancer through epithelial-mesenchymal transition via PI3K/Akt/mTOR signaling pathway. [PDF]
PLOS One Editors.
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Combined Arctigenin and Curcumin Treatment Induces Redox and Metabolic Stress, AMPK Phosphorylation, and Apoptotic Signaling in Prostate Cancer Cells. [PDF]
Cho MK, Lee SH, Nam HS, Choi D, Lee YJ.
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