Pharmaceutics, 2022 Arctiin, a lignan glycoside, is isolated from Arctium lappa L. The anticancer effects of arctiin have been demonstrated in several studies. However, no research has been conducted on the anti-migration effect of arctiin in cervical cancer cells.
Chung-Yuan Lee +2 more
exaly +3 more sources
Targeting SIRT1 stability: arctiin ameliorates doxorubicin-induced cardiac injury by inhibiting SMURF2 binding and enhancing protective lipid metabolism [PDF]
Frontiers in PharmacologyBackgroundDoxorubicin (DOX) is a highly effective chemotherapeutic agent, but its severe cardiotoxicity limits its clinical use. This study aimed to investigate whether the natural compound Arctiin can alleviate DOX-induced cardiomyopathy and its ...
Teng Teng +15 more
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Arctiin-reinforced antioxidant microcarrier antagonizes osteoarthritis progression [PDF]
Journal of Nanobiotechnology, 2022 Loss of extracellular matrix (ECM) of cartilage due to oxidative stress injury is one of the main characteristics of osteoarthritis (OA). As a bioactive molecule derived from the traditional Chinese Burdock, arctiin exerts robust antioxidant properties ...
Yang Liu +11 more
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An insight into the anticancer potentials of lignan arctiin: A comprehensive review of molecular mechanisms [PDF]
HeliyonNatural products are being developed as possible treatment options due to the rising prevalence of cancer and the harmful side effects of synthetic medications.
Raihan Chowdhury +9 more
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Immunopharmacological potential of Arctium lappa L. in immune-mediated skin diseases: A critical review of experimental and clinical evidence [PDF]
Frontiers in PharmacologyBackgroundArctium lappa L. (A. lappa) has been used in traditional medicine worldwide and is increasingly being investigated for its immunomodulatory and anti-inflammatory effects.
Mengyao Yang +16 more
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Frontiers in Microbiology, 2021 Fructus arctii is commonly used in Chinese medicine, and arctiin and arctigenin are its main active ingredients. Arctiin has low bioavailability in the human body and needs to be converted into arctigenin by intestinal microbes before it can be absorbed ...
Zheng Lu
exaly +3 more sources
Effects of Gingerbread Cookie Enrichment with Native and Supercritical CO2-Defatted Burdock Seeds [PDF]
FoodsBurdock (Arctium lappa L., Asteraceae) seeds, a rich source of dietary fibre, proteins, essential and fatty acids, also contain high levels of polyphenols and lignans, especially arctigenin and arctiin. This study investigated the incorporation of native
Katarina Šavikin +7 more
doaj +2 more sources
Arctiin-encapsulated DSPE-PEG bubble-like nanoparticles inhibit alveolar epithelial type 2 cell senescence to alleviate pulmonary fibrosis via the p38/p53/p21 pathway [PDF]
Frontiers in Pharmacology, 2023 Background: Idiopathic pulmonary fibrosis is a severe and deadly form of diffuse parenchymal lung disease and treatment options are few. Alveolar epithelial type 2 (AEC2) cell senescence is implicated in the pathogenies of IPF. A major bioactive compound
Dian Xiong +13 more
doaj +2 more sources
Network pharmacology and computer-aided drug design to explored potential targets of Lianhua Qingwen and Qingfei Paidu decoction for COVID-19 [PDF]
Frontiers in Pharmacology, 2022 Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2, has spread globally, affecting people’s lives worldwide and hindering global development. Traditional Chinese Medicine (TCM) plays a unique role in preventing and treating COVID-19. Representative
Liyuan Li +8 more
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Arctiin, a lignan compound, enhances adipose tissue browning and energy expenditure by activating the adenosine A2A receptor [PDF]
Molecular MedicineBackground The activation of brown adipose tissue (BAT) or the browning of white adipose tissue (WAT) represents a promising therapeutic strategy for obesity.
Yuanfeng Gu +12 more
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