Results 41 to 50 of about 693 (149)

Metabolomic Analysis Reveals the Metabolic Diversity of Wild and Cultivated Stellaria Radix (Stellaria dichotoma L. var. lanceolata Bge.)

Plants, 2023
Stellaria Radix, called Yinchaihu in Chinese, is a traditional Chinese medicine, which is obtained from the dried roots of Stellaria dichotoma L. var. lanceolata Bge.
Zhenkai Li, Hong Wang, Lu Feng, Haishan Li, Yanqing Li, Gege Tian, Pilian Niu, Yan Yang, Li Peng   +8 more
doaj   +1 more source

Phytochemical Investigation for the Main Active Constituents in Arctium lappa L. Cultivated in Iraq

Iraqi Journal of Pharmaceutical Sciences, 2017
Burdock ( Arctium lappa), is among the most popular plants in traditional medicine and it is associated with several biological effects. Literature survey revealed the presence of phenylpropanoid compounds .The most widespread are hydroxycinnamic acids (
Dhuha A.Al-Shammaa, Kawkab Y. Saour, Zaid M. Abdul-Khalik   +2 more
doaj   +3 more sources

Enzyme-hydrolyzed Fruit of : A Rich Source of (-)-(8,8′)-Arctigenin

Natural Product Communications, 2016
In Jurinea mollis fruit, the dibenzylbutyrolactone-type lignan glycoside arctiin and its aglycone arctigenin were determined for the first time using a combination of optimized enzymatic treatment and complementary spectrometric (HPLC-MS, GC-MS) and ...
Rita Könye, Ágnes Evelin Ress, Anna Sólyomváry, Gergő Tóth, András Darcsi, Balázs Komjáti, Péter Horváth, Béla Noszál, Ibolya Molnár-Perl, Szabolcs Béni, Imre Boldizsár   +10 more
doaj   +1 more source

Quality assessment of traditional herbal formula, Hyeonggaeyeongyo-tang through simultaneous determination of twenty marker components by HPLC–PDA and LC–MS/MS

Saudi Pharmaceutical Journal, 2020
Simultaneous analysis of 20 marker components (gallic acid, cimifugin, geniposide, paeoniflorin, ferulic acid, nodakenin, narirutin, naringin, neohesperidin, arctiin, baicalin, oxypeucedanin hydrate, wogonoside, baicalein, arctigenin, glycyrrhizin ...
Chang-Seob Seo, Hyeun-Kyoo Shin
doaj   +1 more source

Importance of interaction between the matrix effect and microbial metabolism in the bioavailability of lignans

Journal of the Science of Food and Agriculture, Volume 106, Issue 4, Page 2180-2189, 15 March 2026.
Abstract BACKGROUND Plant‐lignans are polyphenols with low bioavailability and bioactivity that are transformed by the intestinal microbiota into enterolignans. Our hypotheses are: (i) the way in which plant‐lignans are ingested in the diet affects, in a decisive way, the microbial metabolism of these compounds and (ii) an increase in lignan ...
Susana Langa, José Antonio Curiel, Ruiz de la Bastida, Ángela Peirotén, José María Landete   +4 more
wiley   +1 more source

Advances in Atopic Dermatitis Treatment: From Pathogenesis to Natural Product‐Based Therapies

Phytotherapy Research, Volume 39, Issue 10, Page 4444-4473, October 2025.
NPs improve atopic dermatitis mainly include flavonoids, phenols, glycosides, alkaloids, and others. ABSTRACT Atopic dermatitis (AD), a widespread and chronic inflammatory skin disorder, profoundly affects patients' quality of life, imposes significant psychological strain, and adds to the public health burden.
Xinyun Fan, Zibo Liu, Wenjing Yang, Hongying Zhang, Hao Zhong, Yan Pang, Xun Ye, Chunjie Wu, Liang Li   +8 more
wiley   +1 more source

Dual-function niobium-doped carbon dots for ferroptosis-driven anti-inflammatory therapy in pseudomonas aeruginosa pneumonia via GPX4 axis

Materials & Design
Escalation of antimicrobial resistance (AMR) and the complex pathophysiology of severe hospital-acquired Pseudomonas aeruginosa (PA) pneumonia, driven by a vicious cycle of oxidation-inflammation and ferroptosis, require innovative therapeutic strategies
Na Zhang, Shiqing Yang, Fructueux Modeste Amona, Yongbo Yu, Han Sun, Yuenan Wang, Guangfu Liao, Zheng Gong, Youwei Zhang   +8 more
doaj   +1 more source

Centaurea lycaonica Extracts Induce Apoptosis in HeLa Human Cervical Cancer Cells via Bax/Bcl‐2 Modulation and Caspase Activation: An LC‐HRMS‐Based Study

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
This study highlights the pharmacological mechanisms of dichloromethane (CHD) and methanol (CHM) extracts of Centaurea lycaonica Boiss. & Heldr. herba as the induction of apoptosis on HeLa cells. Apoptotic properties of CHD and CHM are through suppression of Bcl‐2 and increase in Bax, caspase 9, and 3 activities on HeLa cells.
Ayşe Kübra Karaboğa Arslan, Safa Eminoğlu, Leyla Paşayeva, Nuh Mehmet Bozkurt, Osman Tugay   +4 more
wiley   +1 more source

In vivo and in silico investigation of selected herbal compounds as anti-tubercular agents [PDF]

, 2017
Purpose: To investigate whether some herbal compounds, namely, arctiin, NSC333050, cnicin, and arctigenin, can be used as anti-tubercular agents using in vivo and in silico techniques.Methods: A set of structurally diverse herbal compounds were screened ...
Wu, Bin, Chen, Jun-Feng, Jin, Guang-Jun
core   +1 more source

STAT3 Signaling Pathway in Health and Disease

MedComm, Volume 6, Issue 4, April 2025.
An image depicting the role of STAT3 in various human diseases ABSTRACT Signal transducer and activator of transcription 3 (STAT3) is a critical transcription factor involved in multiple physiological and pathological processes. While STAT3 plays an essential role in homeostasis, its persistent activation has been implicated in the pathogenesis of ...
Md Abdus Samad, Iftikhar Ahmad, Aakifah Hasan, Mohammad Hassan Alhashmi, Arusha Ayub, Fahad A. Al‐Abbasi, Ajoy Kumer, Shams Tabrez   +7 more
wiley   +1 more source