Results 31 to 40 of about 693 (149)

Combination of HPLC–orbitrap‐MS/MS and network pharmacology to identify the anti‐inflammatory phytochemicals in the coffee leaf extracts

Food Frontiers, Volume 4, Issue 3, Page 1395-1412, September 2023., 2023
We identified the anti‐inflammatory bioactive components in coffee leaves using HPLC‐Orbitrap‐MS/MS combined with network pharmacology and investigated the significance of the influencing factors. Our results showed that extraction solvent is the most important factor affecting the anti‐inflammatory activity of coffee leaf extract and the bioactive ...
Suhuan Mei, Xiumin Chen
wiley   +1 more source

STAT3 pathway in cancers: Past, present, and future

MedComm, Volume 3, Issue 2, June 2022., 2022
Since the discovery of the signal transducer and activator of transcription 3 (STAT3) in 1994, the STAT3 pathway has been proven to play a pivotal role in cancer initiation, progression, and metastasis. This review summarizes the mechanisms of the STAT3 pathway regulation and the relationship between the STAT3 pathway and cancer hallmarks. The emerging
Han‐Qi Wang, Qi‐Wen Man, Fang‐Yi Huo, Xin Gao, Hao Lin, Su‐Ran Li, Jing Wang, Fu‐Chuan Su, Lulu Cai,, Yi Shi, Bing Liu,, Lin‐Lin Bu   +11 more
wiley   +1 more source

Establishment of Quality Evaluation Method for Yinqiao Powder: A Herbal Formula against COVID‐19 in China

Journal of Analytical Methods in Chemistry, Volume 2022, Issue 1, 2022., 2022
Yinqiao powder, with significant anti‐inflammatory and antiviral effects, is a classical formula for the treatment of febrile diseases in China. During the SARS period in 2003, Yinqiao powder showed a good antipyretic effect. It also plays a major role in the treatment for COVID‐19 in China.
Huimin Zhang, Lin Xu, Jian Song, Aijun Zhang, Xiao Zhang, Qingjun Li, Xinyan Qu, Ping Wang, Mohamed Abdel-Rehim   +8 more
wiley   +1 more source

Study the Mechanism of Gualou Niubang Decoction in Treating Plasma Cell Mastitis Based on Network Pharmacology and Molecular Docking

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
Objective. Explore the potential molecular mechanisms behind the therapeutic functions of Gualou Niubang decoction (GLNBD) in the treatment of plasma cell mastitis (PCM) by network pharmacology and molecular docking. Methods. GLNBD is a formula of Chinese traditional medicine consisting of 12 herbs.
Zhaojing Wu, Qing Yang, Hongbo Ma, Arif Jamal Siddiqui   +3 more
wiley   +1 more source

Spectrum‐effect relationship between UPLC fingerprints and anti‐lung cancer effect of Panax ginseng

Phytochemical Analysis, Volume 32, Issue 3, Page 339-346, May/June 2021., 2021
Abstract Objectives Lung cancer has the highest mortality rate among the various types of cancer. Panax ginseng (C. A. Mey). is a popular anti‐cancer herbal supplement. The quality control of ginseng is crucial to ensure its clinical efficacy. This study aimed to establish new quality control methods for ginseng and to identify its main active ...
Xiaowei Zhou, Haiyang Liu, Mingyu Zhang, Chunyu Li, Guohui Li   +4 more
wiley   +1 more source

Network Pharmacology‐Based Strategy and Molecular Docking to Explore the Potential Mechanism of Jintiange Capsule for Treating Osteoporosis

Evidence-Based Complementary and Alternative Medicine, Volume 2021, Issue 1, 2021., 2021
Background. With the advent of ageing population, osteoporosis (OP) has already become a global challenge. Jintiange capsule is extensively applied to treat OP in China. Although recent studies demonstrate that it generates significant effects on strengthening bone, the exact mechanism of the jintiange capsule for treating OP remains unknown.
Zhao Yang, Zhen-Zhen Yuan, Xin-Long Ma, Saheed Sabiu   +3 more
wiley   +1 more source

Optimization of Aqueous Extraction Conditions of Inulin from the Arctium lappa L. Roots Using Ultrasonic Irradiation Frequency

Journal of Food Quality, Volume 2021, Issue 1, 2021., 2021
Ultrasound‐assisted extraction is a promising technique to obtain active compounds from plants with high efficiency. The present study was conducted in two sections. In the first phase, the effect of solvent type (methanol, ethanol, water, and water‐ethanol (50 : 50, v/v)) on inulin extraction yield from burdock roots (Arctium lappa L.) was ...
Farzaneh Esmaeili, Mahnaz Hashemiravan, Mohammad Reza Eshaghi, Hassan Gandomi, Milan Stankovic   +4 more
wiley   +1 more source

Additional file 1 of Arctiin-reinforced antioxidant microcarrier antagonizes osteoarthritis progression

, 2022
Additional file 1. Figure S1. (A-B) The protein levels of COLII, ACAN, MMP13, ADAMTS5, SOD1, SOD2, CAT, GPX1, and NRF2 were determined using Western blot assays. Figure S2.
Tao Liu (10785), Zhijian Zhao (389825), Qin Shi (569321), Yijian Zhang (404766), Fan He (303535), Zejun Pan (12967976), Xin Tian (29048), Huilin Yang (303871), Yang Liu (4829), Mingzhuang Hou (11691836), Xi Chen (35903), Xuesong Zhu (569319)   +11 more
core   +1 more source

Biosynthesis of lignans. Part I . Biosynthesis of Arctiin (3) and Phillyrin (5) [PDF]

, 1977
Lignans constitute a class of naturally occuring phenolic compounds, widely distributed in higher plants. They are formally composed of two phenylpropanoid units, stercospecifically joined at the /f-carbon atoms of their side chains. Their biosynthesis
Klischies, Martina, Stöckigt, Joachim
core   +1 more source

Isolation and Characterization of Bioactive Compounds from Scotch Thistle (Onopordum acanthium L.) Seeds [PDF]

Pharmaceutical Sciences
Background: Scotch thistle (Onopordum acanthium L.) is a medicinal food plant known for its phytochemical diversity. Methods: In this study, methanolic and petroleum ether extracts of Scotch thistle seeds were subjected to phytochemical analysis.
Sakineh Mohammadi, Ali Movefeghi, Abbas Delazar, Sanaz Hamedeyazdan, Mir Babak Bahadori, Hossein Nazemiyeh   +5 more
doaj   +1 more source