Results 21 to 30 of about 693 (149)

Liver-Targeting Nanoparticles GA-MSe@AR Treat NAFLD Through Dual Lipid-Lowering and Antioxidant Efficacy [PDF]

International Journal of Nanomedicine
Sheng Lei,1 Qiang Wu,1 Bin Zhang,1 Minqiang Lu,1 Yu Xia,1,2 Ning Li1 1Department of HBP Surgery, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, 510180, People’s Republic of China; 2Department of ...
Lei S, Wu Q, Zhang B, Lu M, Xia Y, Li N
doaj   +2 more sources

Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro

World Journal of Traditional Chinese Medicine
Objective: Osteoarthritis (OA) is a progressive joint disease characterized by degeneration and destruction of articular cartilage. Arctiin (ARC) has been shown in many studies to have potential anti-inflammatory, anti-apoptotic, and antioxidant effects ...
Yong-Jia Song, Jia-Min Bao, Zeng-Qiao Zhang, Yun-Xiang Hai, Hao-Nan Wen, Tian-Jun Zhai, Wei Feng, Min Song   +7 more
doaj   +2 more sources

Phytochemical analysis and antioxidative properties of Centaurea albonitens [PDF]

Research Journal of Pharmacognosy, 2017
Background and objectives: Thegenus Centaurea from the Asteraceae family is one of the most widely distributed plant genera worldwide that has been extensively used in folk medicine for hundreds of years.
S. Hamedeyazdan, F. Niroumand, F. Fathiazad   +2 more
doaj   +2 more sources

Network pharmacology and metabolomics reveal mathurameha, a Thai traditional Anti-Diabetic formula, enhances glucose metabolism through PI3K-AKT/AMPK/GLUT4 pathway modulation [PDF]

Scientific Reports
Traditional herbal formulations offer promising avenues for diabetes management by targeting multiple molecular pathways. Mathurameha (MT), a polyherbal preparation, has been historically used for its antidiabetic potential.
Subhadip Banerjee, Wuttichai Jaidee, Narawadee Rujanapun, Thidarat Duangyod, Tharakorn Maneerat, Pravaree Phuneerub, Kulwadee Malee, Siam Popluechai, Virayu Suthiphasilp, Panupong Puttarak, Poonsit Hiransai, Surat Laphookhieo, Salfarina Ramli, Wim Vanden Berghe, Geoffrey A. Cordell, Rawiwan Charoensup   +15 more
doaj   +2 more sources

Arctiin Alleviates Atopic Dermatitis Against Inflammation and Pyroptosis Through Suppressing TLR4/MyD88/NF-κB and NLRP3/Caspase-1/GSDMD Signaling Pathways [PDF]

Journal of Inflammation Research
Jingmin Li,1,2 Xuefei Du,1 Zhenzhen Mu,1 Xiuping Han1 1Department of Dermatology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, People’s Republic of China; 2Department of Dermatology, Third Hospital of Shanxi Medical University ...
Li J, Du X, Mu Z, Han X
doaj   +1 more source

Arctiin targets oxidative stress and inflammation, restores Neuregulin-1, and improves neurobehavioral outcomes in neonatal hypoxic-ischemic brain injury. [PDF]

Curr Res Pharmacol Drug Discov
OBJECTIVE: Hypoxic-ischemic brain damage (HIBD) represents a major cause of neonatal morbidity and mortality, resulting from perinatal oxygen deprivation and impaired cerebral blood flow.
Babak S, Safari T, Fanaei H.
europepmc   +2 more sources

Arctiin alleviates knee osteoarthritis by suppressing chondrocyte oxidative stress induced by accumulated iron via AKT/NRF2/HO-1 signaling pathway [PDF]

Scientific Reports
Iron overload (IO) was considered to be a risk factor for cartilage degradation in knee osteoarthritis (KOA) advancement. However, few drugs were found to improve cartilage degeneration by alleviating multiple cell death induced by the impaired iron ...
Junzheng Yang, Delong Chen, Qi He, Baihao Chen, Zhaofeng Pan, Gangyu Zhang, Miao Li, Shaocong Li, Jiacong Xiao, Haibin Wang, Peng Chen, Zhantian An   +11 more
doaj   +2 more sources

Arctiin suppresses H9N2 avian influenza virus-mediated inflammation via activation of Nrf2/HO-1 signaling

BMC Complementary Medicine and Therapies, 2021
Background H9N2 avian influenza viruses (AIVs) infect avian and mammalian hosts and provide internal genes for new emerging highly pathogenic avian viruses that cause severe pneumonia with high mortality, for which few medications are available. Arctiin,
Beixian Zhou, Linxin Wang, Yueyun Liang, Jing Li, Xiping Pan   +4 more
doaj   +1 more source

Unraveling the signaling mechanism behind astrocytoma and possible therapeutics strategies: A comprehensive review

Cancer Reports, Volume 6, Issue 10, October 2023., 2023
Abstract Background A form of cancer called astrocytoma can develop in the brain or spinal cord and sometimes causes death. A detailed overview of the precise signaling cascade underlying astrocytoma formation has not yet been revealed, although various factors have been investigated.
Chowdhury Lutfun Nahar Metu, Sunita Kumari Sutihar, Md Sohel, Fatematuz Zohora, Akayed Hasan, Md. Thandu Miah, Tanu Rani Kar, Md. Arju Hossain, Md Habibur Rahman   +8 more
wiley   +1 more source

Lianhua Qingke ameliorates lipopolysaccharide‐induced lung injury by inhibiting neutrophil extracellular traps formation and pyroptosis

Pulmonary Circulation, Volume 13, Issue 4, October 2023., 2023
Abstract LHQK is a patented Traditional Chinese Medicine (TCM) which is clinically used for acute tracheobronchitis, cough, and other respiratory diseases. Recent studies have proved that LHQK exhibits excellent clinical efficacy in the treatment of acute lung injury (ALI). However, the corresponding mechanisms remain largely unexplored. In this study,
Wenjun Peng, Hui Qi, Wensi Zhu, Lin Tong, Ainiwaer Rouzi, Yuanyuan Wu, Linxiao Han, Ludan He, Yu Yan, Ting Pan, Jie Liu, Qin Wang, Zhenhua Jia, Yuanlin Song, Qiaoliang Zhu, Jian Zhou   +15 more
wiley   +1 more source