Results 161 to 170 of about 599,754 (328)

Arcuate nucleus – a gateway for insulin's action on sympathetic activity

The Journal of Physiology, 2011
Landsberg and colleagues in the 1980s first showed that an increase in the level of circulating insulin results in an increase in sympathetic activity, both in humans and in rats, even under conditions where the level of plasma glucose is clamped (for review see Landsberg, 2001).
openaire   +3 more sources

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Hybrid Heterostructures of Nanostructured Si Membrane and MoS2 for Self‐Powered Photodetectors

Advanced Electronic Materials, EarlyView.
A scalable MoS2/Si nanomesh vertical heterostructure is developed for self‐powered photodetection. The nanostructured junction enhances conductivity, expands the active heterointerface, and enables a transition from photovoltaic to avalanche‐assisted operation, delivering markedly improved photoresponse over planar counterparts.
Jingying Liu, Zhichen Wan, Haoran Mu, Siqi Deng, Mohammad M. Hossain, Udo Bach, Shenghuang Lin, Qingdong Ou, Sudha Mokkapati   +8 more
wiley   +1 more source

Methodology for Studying Hypothalamic Regulation of Feeding Behaviors

Methods and Protocols
Continuous advances in neurological research techniques are enabling researchers to further understand the neural mechanisms that regulate energy balance.
Julia B. Davenport, Ali D. Güler, Qi Zhang   +2 more
doaj   +1 more source

InGaP/GaAs/InGaAs Multijunction Flexible Photovoltaics With Chemical Robustness and Radiation Hardness for Unassisted Electrocatalysis and Space Applications

Advanced Energy Materials, EarlyView.
A flexible InGaP/GaAs/InGaAs triple‐junction platform encapsulated with ultrathin glass enables unassisted electrocatalysis and space applications by providing robust protection against chemically aggressive and radiation‐rich environments. This work establishes a unified III–V multijunction photovoltaic platform that bridges space photovoltaics and ...
Sukkyu Hong, Seungwan Woo, Hoki Son, Hyun‐Beom Shin, Eungbeom Yeon, Jeongeun Mo, Daehwan Jung, Ho Won Jang, Ho Kwan Kang, Sung‐Min Lee, Won Jun Choi   +10 more
wiley   +1 more source

Probing Steady‐State Carrier Properties and Charge Transport in Covalent Organic Framework by Frequency‐Domain Terahertz Spectroscopy

Angewandte Chemie, EarlyView.
This work reports a combined frequency‐domain and time‐domain terahertz (THz) spectroscopic approach to elucidate intrinsic carrier properties and transport mechanisms in framework materials over the extended 0.5–20 THz region. Subtle structural and chemical variations are shown to strongly influence THz charge‐transport behavior across the far ...
Satyapriya Nath, Saiprakash Rout, Mahalaxmi Samal, Snehal Haldankar, Md Habib Ahsan, Anol Mondal, Sudeep Tiwari, Adithyan Puthukkudi, Avani KV, Ashis K. Nandy, Shriganesh S. Prabhu, Himansu S. Biswal, Xinliang Feng, Bishnu P. Biswal   +13 more
wiley   +2 more sources

Foreign Language Learning in Older Adults Modifies Resting‐State Functional Connectivity Between the Subcortical Structures and the Cortex

AGING MEDICINE, EarlyView.
Foreign language learning in older adults reorganizes thalamic and caudate connectivity, in a process topographically overlapping with the expression of receptors and genes related to neuroplasticity. ABSTRACT Objectives Neuroimaging studies suggest that Foreign Language Learning (FLL) influences resting‐state functional connectivity (rs‐FC) within the
Giovanna Bubbico, Federica Tomaiuolo, Carlo Sestieri, Golnoush Akhlaghipour, Alberto Granzotto, Antonio Ferretti, Mauro Gianni Perrucci, Stefano L. Sensi, Stefano Delli Pizzi   +8 more
wiley   +1 more source

Self‐Limiting Polymerization‐Induced Crystallization‐Driven Self‐Assembly (SL‐PI‐CDSA) Enables Templated Synthesis of Chiral Plasmonic, Hybrid 2D Hexagonal Assemblies

Angewandte Chemie, EarlyView.
This work details the rapid generation (t ≤ 5 min) of size‐tunable, ultralow dispersity (Ð ≤ 1.01) 2D hexagonal nanosheets by self‐limiting polymerization‐induced crystallization‐driven self‐assembly (SL‐PI‐CDSA) of modular and templating poly(aryl isocyanide) block copolymers, with functions that permit post‐polymerization modifications. Specifically,
Randall A. Scanga, Sean H. Sarault, Amin Kiani, Patryk Wąsik, Anthony J. Branco, Sophie A. Harris, Sangmin Jeong, Ali Shahrokhinia, Jake Borges, Cassidy M. Anunciacao, Jayant Kumar, Lawrence M. Wolf, Michael B. Ross, James F. Reuther   +13 more
wiley   +2 more sources

Swallowing and Communication in Cockayne Syndrome: Clinical Characteristics and Management

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cockayne syndrome (CS) is an ultrarare genetic disorder associated with genes encoding proteins involved in DNA repair. The clinical course of CS involves neurodevelopmental and neurodegenerative features, including swallowing and communication impairments.
Abigail M. Spoden, Katlyn E. McGrattan, Peter B. Kang   +2 more
wiley   +1 more source

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

Animal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong, Wei Qian, Deji Song, Kang Li, Li Zhang, Li Shi   +5 more
wiley   +1 more source