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Regulation of Arcuate Nucleus Synaptology by Estrogena

Annals of the New York Academy of Sciences, 1994
Estrogen modulates the synaptology of the hypothalamic arcuate nucleus during sexual differentiation of the rat brain in both males and females. In males, testosterone of gonadal origin is converted to estrogen in the brain by an enzyme, aromatase, which is also present in females.
L, Leedom   +3 more
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Outline of the arcuate nucleus in the human medulla oblongata

Cells Tissues Organs, 1975
The outline of the arcuate nucleus in the human medulla oblongata was studied in a series of serial sections of brain stems of newborn and young children. The nucleus lies on the ventral aspect of the pyramid. At higher levels the nucleus lies on the ventral and medial aspect of the pyramid.
Y, Mikhail, Y Y, Ahmed
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Arcuate nucleus of the hypothalamus: Effects of age and sex

The Journal of Comparative Neurology, 1998
The arcuate nucleus of the hypothalamus (ARN) is involved in a variety of functions known to be sexually dimorphic and altered by aging. Although the effects of sex and age on the synaptic organization and neurochemistry of the ARN have been extensively analyzed, data regarding sex-related differences and age-induced effects on the total number of ...
S, Leal   +3 more
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Hormonal regulation of the arcuate nucleus melanocortin system

Frontiers in Bioscience, 2007
Over the past century, the hypothalamus has emerged as one of the critical sites involved in energy homeostasis. Degeneration studies in rats performed some six decades ago, first led to identifying hypothalamic subregions controlling food intake and body weight.
Anna, Coppola, Sabrina, Diano
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Ovary-Dependent Degeneration in the Hypothalamic Arcuate Nucleus*

Endocrinology, 1980
The effects of estradiol valerate and constant light exposure on the histological appearance of the arcuate nucleus were assessed in female rats. Both of these treatments caused significant increases in the numbers of reactive microglial cells and astrocytic granules in the nucleus.
J R, Brawer, H, Schipper, F, Naftolin
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Integration of metabolic stimuli in the hypothalamic arcuate nucleus

2006
Integration of peripheral and central anabolic and catabolic inputs within the hypothalamic arcuate nucleus (ARC) is believed to be central to the maintenance of energy balance. In order to perform this complex task, neurons in the ARC express receptors for all major humoral and central transmitters involved in the maintenance of energy homeostasis ...
M, van den Top, D, Spanswick
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Arcuate nucleus, median eminence, and hypophysial pars tuberalis

2021
The arcuate nucleus (ARC) is located in the mediobasal hypothalamus and forms a morphological and functional entity with the median eminence (ME), the ARC-ME. The ARC comprises several distinct types of neurons controlling prolactin release, food intake, and metabolism as well as reproduction and onset of puberty. The ME lacks a blood-brain barrier and
Korf, Horst Werner, Møller, Morten
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Dynorphin in pro-opiomelanocortin neurons of the hypothalamic arcuate nucleus

Neuroscience, 2008
Considerable evidence suggests that dynorphin participates in the regulation of energy balance. In this study, we have used immunohistochemistry to investigate in detail the cellular localization of pro-dynorphin (DYN) immunoreactive cell bodies in the mediobasal hypothalamus with special reference to neurons producing orexigenic or anorexigenic ...
N, Maolood, B, Meister
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Rapid Rewiring of Arcuate Nucleus Feeding Circuits by Leptin

Science, 2004
The fat-derived hormone leptin regulates energy balance in part by modulating the activity of neuropeptide Y and proopiomelanocortin neurons in the hypothalamic arcuate nucleus. To study the intrinsic activity of these neurons and their responses to leptin, we generated mice that express distinct green fluorescent proteins in these two ...
Pinto S   +7 more
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Advances in appetite regulation by the arcuate nucleus

Nature Reviews Endocrinology
In 2024, new insights identified a cluster of leptin-targeted neurons and integrative networks that link sensory inputs (heat and food perception) with feeding centres and peripheral systems. Key findings revealed hypothalamic site-specific adaptive mechanisms, in which nutritional state-dependent remodelling of extracellular compounds and neuropeptide
openaire   +3 more sources

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