Results 301 to 310 of about 599,754 (328)
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Estrogen Promotes Parvalbumin Expression in Arcuate Nucleus POMC Neurons
Reproductive Sciences, 2010We have found that estrogen promotes suppression of feeding and a lean body mass while activating the arcuate nucleus proopiomelanocortin (POMC)-expressing neurons. These neurons, when activated, suppress appetite and increase energy expenditure. Because the increased activation of POMC neurons by estradiol was associated with increased glutamate ...
Peter, Sotonyi +3 more
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Electrophysiological evidence for a projection from the arcuate nucleus to the supraoptic nucleus
Neuroscience Letters, 1988The electrical activity of single neurones in the hypothalamic arcuate and supraoptic nuclei was recorded in urethane-anaesthetized rats. Stimulus pulses applied to the supraoptic nucleus antidromically activated 3 out of 41 cells recorded in the ipsilateral arcuate nucleus, confirming that there is a projection from the arcuate nucleus to the region ...
G, Leng +3 more
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GABAergic projection from the arcuate nucleus to the supraoptic nucleus in the rat
Neuroscience Letters, 2000Electrical stimulation of the neurones in the hypothalamic arcuate nucleus results in a transient inhibition followed by a marked post-stimulus excitation of magnocellular neurones of the supraoptic nucleus. Microdialysis administration of the gamma-aminobutyric acid agonist (GABA(A)), muscimol, directly into the supraoptic nucleus inhibited both ...
M, Ludwig, G, Leng
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Integration of metabolic stimuli in the hypothalamic arcuate nucleus
2006Integration of peripheral and central anabolic and catabolic inputs within the hypothalamic arcuate nucleus (ARC) is believed to be central to the maintenance of energy balance. In order to perform this complex task, neurons in the ARC express receptors for all major humoral and central transmitters involved in the maintenance of energy homeostasis ...
M, van den Top, D, Spanswick
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Dynorphin in pro-opiomelanocortin neurons of the hypothalamic arcuate nucleus
Neuroscience, 2008Considerable evidence suggests that dynorphin participates in the regulation of energy balance. In this study, we have used immunohistochemistry to investigate in detail the cellular localization of pro-dynorphin (DYN) immunoreactive cell bodies in the mediobasal hypothalamus with special reference to neurons producing orexigenic or anorexigenic ...
N, Maolood, B, Meister
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Intranuclear crystalloids in arcuate nucleus neurons after clomiphene citrate administration
Experientia, 1986The action of high doses of clomiphene citrate on the nuclei of hypothalamic arcuate neurons of male cats has been studied. Clomiphene produces an accumulation of typical crystalloid material in the nuclei. After administration of a protein-synthesis inhibitor, no such material was observed in clomiphene-treated animals.
M, Alvarez-Uria +2 more
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Glucocorticoid regulation of proopiomelanocortin mRNA levels in rat arcuate nucleus
Molecular and Cellular Neuroscience, 1990The role of glucocorticoids in the regulation of proopiomelanocortin (POMC) mRNA levels in the hypothalamus was studied in different areas of the arcuate nucleus using quantitative in situ hybridization. The arcuate nucleus was arbitrarily divided into four regions in a rostral to caudal plane and the levels of mRNA were measured by optical ...
Y, Tong +3 more
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Arcuate Nucleus Region in Androgen-Sterilized Female Rats: Ultrastructural Observations
Neuroendocrinology, 1971The effects of early postnatal treatment with testosterone propionate (TP) on the ultrastructure of the arcuate region, comprising the arcuate nucleus and adjacent median eminence, of adult anovulatory female rats were studied. Nerve propionate terminals ending on arcuate neurons in the TP-treated animals exhibited a decrease in dense-core vesicles ...
A, Ratner, N J, Adamo
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Diffusional barrier around the hypothalamic arcuate nucleus in the rat
Brain Research, 1984The contour lines of horseradish peroxidase injection sites in the ventrobasal hypothalamus were distorted by the border between arcuate and ventromedial nuclei as well as between arcuate nucleus and median eminence. The dense array of tanycyte processes is assumed to isolate the arcuate nucleus from the neighboring territories by establishing a ...
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Generation of hypothalamic arcuate organoids from human induced pluripotent stem cells
Cell Stem Cell, 2021Feng Zhang, Daniel Y Zhang, Wanqi Fang
exaly