Results 141 to 150 of about 13,679,454 (317)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Transforming Area Coverage to Target Coverage to Maintain Coverage and Connectivity for Wireless Sensor Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2012
Area coverage is one of the key issues for wireless sensor networks. It aims at selecting a minimum number of sensor nodes to cover the whole sensing region and maximizing the lifetime of the network.
Xiu Deng   +3 more
doaj   +1 more source

Optimal Coverage Level Choice with Individual and Area Plans of Insurance [PDF]

open access: yes
We theoretically examine a farmer’s coverage demand with area and individual insurance plans as either separate or integrated options. The individual and area losses are assumed to be imperfectly and positively correlated.
Bulut, Harun   +2 more
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Global protected-area coverage and human pressure on tidal flats. [PDF]

open access: yesConserv Biol, 2021
Hill NK   +4 more
europepmc   +1 more source

Coverage Area Optimized Static Reflecting Surfaces

open access: yesIEEE Transactions on Wireless Communications
Publisher Copyright: © 2024 IEEE.
Al-Tous Hanan, Tirkkonen Olav
openaire   +2 more sources

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