Results 111 to 120 of about 1,295,849 (308)

Estimating the Area under a Receiver Operating Characteristic Curve For Repeated Measures Design

open access: yes
The receiver operating characteristic (ROC) curve is widely used for diagnosing as well as for judging the discrimination ability of different statistical models.
Honghu Liu, Tongtong Wu
core  

Estimating open economy Phillips curves for the euro area with directly measured expectations [PDF]

open access: yes
This paper examines euro area inflation dynamics by estimating open economy New Keynesian Phillips curves based on the assumption that all imports are intermediate goods. Instead of imposing rational expectations a priori, Consensus Economics survey data
Paloviita, Maritta
core  

Area under the operating characteristics curve.

open access: yes, 2015
Area under the operating characteristics curve.
Jian Liao (20886)   +12 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

The yield curve as a predictor and emerging economies [PDF]

open access: yes
This paper investigates the extent to which the slope of the yield curve in emerging economies predicts domestic inflation and growth. It also examines international financial linkages and how the US and euro area yield curves help to predict.
Mehl, Arnaud
core  

Area Under the Receiver Characteristics Curve (AUROC).

open access: yes
Discriminatory performance of models A: the area under the receiver characteristics curve (AUROC) of men; B: the area under the receiver characteristics curve (AUROC) of women.
Geneviève Gariépy (495491)   +10 more
core   +1 more source

Area under Curve (AUC) comparison.

open access: yes, 2013
Area under Curve (AUC) comparison measuring the ability of recovering the original PPI networks: (a) Y_Tong, (b) H_Bind, (c) H_InAct, (d) F_BioGrid, (e) H_BioGrid using embedding space dimensions of 1 to 20.
Lin Zhu (192179)   +3 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Single‐dose pharmacokinetic study comparing the pharmacokinetics of recombinant human chorionic gonadotropin in healthy Japanese and Caucasian women and recombinant human chorionic gonadotropin and urinary human chorionic gonadotropin in healthy Japanese women

open access: yesReproductive Medicine and Biology, 2018
Purpose Recombinant hCG (r‐hCG) was approved in Japan in 2016. As a prerequisite for a Phase III study in Japan related to this approval, the pharmacokinetic (PK) profile of r‐hCG was investigated. Methods An open‐label, partly randomized, single‐center,
Wilhelmina Bagchus   +2 more
doaj   +1 more source

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