Results 101 to 110 of about 1,295,849 (308)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Cut-off Values for Lower Limb Muscle Thickness to Detect Low Muscle Mass for Sarcopenia in Older Adults

Clinical Interventions in Aging, 2021
Yoshihiro Fukumoto,1,2 Tome Ikezoe,2 Masashi Taniguchi,2 Yosuke Yamada,3 Shinichiro Sawano,4 Seigo Minani,5 Tsuyoshi Asai,6 Misaka Kimura,7,8 Noriaki Ichihashi2 1Department of Physical Medicine and Rehabilitation, Kansai Medical University, Hirakata ...
Fukumoto Y, Ikezoe T, Taniguchi M, Yamada Y, Sawano S, Minani S, Asai T, Kimura M, Ichihashi N   +8 more
doaj  

c-statistic (area under curve) = .705.

, 2016
c-statistic (area under curve) = .705.
Jingqiang Zhu (2579947), Ding Yuan (142530), Jichun Zhao (120536), Bin Huang (331329), Han Luo (302386), Hongliu Yang (772489)   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The area under curve for time-course analysis parameters is associated with abdominal aortic aneurysms and the severity of peripheral artery disease in men. [PDF]

Int J Cardiol Hypertens, 2021
Konno N, Harada T, Akamatsu D, Goto H, Miki T, Kamei T, Kohzuki M.   +6 more
europepmc   +1 more source

The area under the ROC curve.

, 2019
The area under the ROC curve.
Fitsum Mesfin Zewudie (7115054), Girum Tesfaye Kiya (7115051)   +1 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Smartphone addiction and sleep quality among nursing students in Meknes, Morocco: A cross-sectional study

Belitung Nursing Journal
Background: Smartphone addiction and poor sleep quality are prevalent health concerns that negatively impact students’ physical and mental well-being, which could affect their academic performance.
Abdelhadi El Haddaouy, Youssef Miyah, Mohammed Benjelloun, Aziz Mengad, Hicham Blaak, Hayat Iziki, Fatima El Omari   +6 more
doaj   +1 more source

Area under the curve of immunosuppressants.

, 2016
Area under the curve of immunosuppressants.
Susanne Stampf (3387182), Stefan Schaub (93526), Karen Molyneux (3387176), Jonathan Barratt (3387179), Michael T. Koller (2735299), Min Jeong Kim (234956)   +5 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source