Results 91 to 100 of about 1,302,973 (308)
Pharmacokinetics of cyclosporin: a microemulsion in children with idiopathic nephrotic syndrome
Clinics, 2012 OBJECTIVE: We present a prospective study of a microemulsion of cyclosporin to treat idiopathic nephrotic syndrome in ten children with normal renal function who presented cyclosporin trough levels between 50 and 150 ng/ml and achieved complete remission
Luciana dos Santos Henriques +2 more
doaj +1 more source
On splitting the area under curves
Journal of Differential Equations, 1977 AbstractTwo area-splitting problems involving real-valued functions of a real variable are investigated. The second of these is essentially equivalent to finding all functions a ϵ C1((0, r)) with 0 < a(x) < x which satisfy the functional differential equation a′ (a(x)) = a(x)x for x ϵ (0, r). All solutions analytic at x = 0 (and many which are not) are
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Phillips curve under state-dependent pricing [PDF]
This paper is related to a large recent literature studying the Phillips curve in sticky-price equilibrium models. It differs in allowing for the degree of price stickiness to be determined endogenously. A closed-form solution for short-term inflation is
Bakhshi Hasan +2 more
core
Exact Probability Distribution for the ROC Area under Curve. [PDF]
Cancers (Basel), 2023 Ekström J +2 more
europepmc +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Is the Area Under Curve Appropriate for Evaluating the Fit of Psychometric Models? [PDF]
Educ Psychol Meas, 2023 Han Y, Zhang J, Jiang Z, Shi D.
europepmc +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Python software for calculating the area under a curve [PDF]
, 2019 Area under the curve represents the summation of a function over an interval, and is of interest in a variety of applications. Typically, the Trapezium rule is used for estimating the area under the curve.
Wenfa Ng (444092)
core +1 more source