Results 91 to 100 of about 1,295,849 (308)

Mean Arterial Pressure, Uterine Artery Doppler and Serum Placental Growth Factor Measured in First Trimester for Prediction of Preeclampsia: A Prospective Observational Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Preeclampsia affects 2 to 5% of pregnant women and is a leading cause of maternal and perinatal morbidity and mortality. Aim: To predict the development of preeclampsia during the first trimester by using mean arterial pressure, uterine ...
K Geetha, Mamatha, Urvashi, MN Vanitha Gowda   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Pharmacokinetics of cyclosporin: a microemulsion in children with idiopathic nephrotic syndrome

Clinics, 2012
OBJECTIVE: We present a prospective study of a microemulsion of cyclosporin to treat idiopathic nephrotic syndrome in ten children with normal renal function who presented cyclosporin trough levels between 50 and 150 ng/ml and achieved complete remission
Luciana dos Santos Henriques, Fabíola de Marcos Matos, Maria Helena Vaisbich   +2 more
doaj   +1 more source

Area-Under-Curve-Guided Versus Trough-Guided Monitoring of Vancomycin and Its Impact on Nephrotoxicity: A Systematic Review and Meta-Analysis. [PDF]

Ther Drug Monit, 2023
Lim AS, Foo SHW, Benjamin Seng JJ, Magdeline Ng TT, Chng HT, Han Z.   +5 more
europepmc   +1 more source

Comparison of model performance using area under the ROC curve (AUROC) and area under the precision-recall curve (AUPR) on DREAM5 data sets.

, 2023
Comparison of model performance using area under the ROC curve (AUROC) and area under the precision-recall curve (AUPR) on DREAM5 data sets.
Zoran Nikoloski (175457), Alain J. Mbebi (16715678)   +1 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Comparison of glucose time in range and area under curve in range in relation to risk of diabetic retinopathy in type 2 diabetes patients. [PDF]

J Diabetes Investig, 2022
Wang Y, Lu J, Shen Y, Ni J, Zhang L, Lu W, Zhu W, Bao Y, Zhou J.   +8 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Validation of HF-Bioelectrical Impedance Analysis versus Body Mass Index in Classifying Overweight and Obese Pakistani Adults

Journal of Multidisciplinary Healthcare, 2023
Rabia Anwer,1 Lubna Ansari Baig,2 Mehjabeen Musharraf3 1Registered Dietitian Nutritionist, PNS Shifa Hospital, Karachi, 75270, Pakistan; 2Chairperson, APPNA Institute of Public Health, Jinnah Sindh Medical University, Karachi, 75510, Pakistan; 3Senior ...
Anwer R, Baig LA, Musharraf M
doaj  

A Statistical Method for Exploratory Data Analysis Based on 2D and 3D Area under Curve Diagrams: Parkinson's Disease Investigation. [PDF]

Sensors (Basel), 2021
Sushkova OS, Morozov AA, Gabova AV, Karabanov AV, Illarioshkin SN.   +4 more
europepmc   +1 more source