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Distinct Biological and Epidemiological Features of Old World and New World Arenaviruses
The Arenaviridae family comprises a diverse group of enveloped, bisegmented, negative-sense RNA viruses that establish persistent infections in rodent hosts and occasionally transmit zoonotically to humans [1-2].
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Taxonomy of the family Arenaviridae and the order Bunyavirales: update 2018 [PDF]
In 2018, the family Arenaviridae was expanded by inclusion of 1 new genus and 5 novel species. At the same time, the recently established order Bunyavirales was expanded by 3 species.
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Experimental infection of Neotoma albigula (Muridae) with Whitewater Arroyo virus (Arenaviridae).
The American journal of tropical medicine and hygiene, 2001The Whitewater Arroyo virus (WWA) is a newly described North American arenavirus. The purpose of this study was to elucidate the biology of this virus in its natural rodent host, Neotoma albigula (white-throated woodrat). Thirteen adult, 7 juvenile, and 8 newborn woodrats each were inoculated subcutaneously with 1,000 cell culture infectious dose50 of ...
C F, Fulhorst +3 more
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The American Journal of Tropical Medicine and Hygiene, 2006
The clinical laboratory, virologic, and pathologic changes occurring in hamsters after infection with Pirital virus (Arenaviridae) are described. Pirital virus infection in the hamsters was characterized by high titered viremia, leukocytosis, coagulopathy, pulmonary hemorrhage and edema, hepatocellular and splenic necrosis, and marked elevation of ...
Elena, Sbrana +5 more
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The clinical laboratory, virologic, and pathologic changes occurring in hamsters after infection with Pirital virus (Arenaviridae) are described. Pirital virus infection in the hamsters was characterized by high titered viremia, leukocytosis, coagulopathy, pulmonary hemorrhage and edema, hepatocellular and splenic necrosis, and marked elevation of ...
Elena, Sbrana +5 more
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The American journal of tropical medicine and hygiene, 2001
Adult Syrian golden hamsters inoculated intraperitoneally with Pirital virus, a recently discovered member of the Tacaribe complex of New World arenaviruses, developed a progressively severe, fatal illness with many of the pathologic features observed in fatal human cases of Lassa fever and other arenaviral hemorrhagic fevers.
S Y, Xiao, H, Zhang, Y, Yang, R B, Tesh
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Adult Syrian golden hamsters inoculated intraperitoneally with Pirital virus, a recently discovered member of the Tacaribe complex of New World arenaviruses, developed a progressively severe, fatal illness with many of the pathologic features observed in fatal human cases of Lassa fever and other arenaviral hemorrhagic fevers.
S Y, Xiao, H, Zhang, Y, Yang, R B, Tesh
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Journal of Immunology
CD4 and CD8 T cells play a key role in clearing Arenaviridae infections, even before the appearance of neutralizing antibodies. Thus, while vaccine strategies that would generate a rapid and durable neutralizing antibody response are desirable, a ...
Yeji Lee, A. Sette, A. Grifoni
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CD4 and CD8 T cells play a key role in clearing Arenaviridae infections, even before the appearance of neutralizing antibodies. Thus, while vaccine strategies that would generate a rapid and durable neutralizing antibody response are desirable, a ...
Yeji Lee, A. Sette, A. Grifoni
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Arenavirus genomics: novel insights into viral diversity, origin, and evolution.
Current Opinion in Virology, 2019Next-generation sequencing technologies have revolutionized our knowledge of virus diversity and evolution. In the case of arenaviruses, which are the focus of this review, metagenomic/metatranscriptomic approaches identified reptile-infecting and fish ...
C. Pontremoli, D. Forni, M. Sironi
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Arenavirus Quasispecies and Their Biological Implications
Current Topics in Microbiology and Immunology, 2015The family Arenaviridae currently comprises over 20 viral species, each of them associated with a main rodent species as the natural reservoir and in one case possibly phyllostomid bats.
A. Grande-Pérez +3 more
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Mammarenavirus Genetic Diversity and Its Biological Implications.
Current Topics in Microbiology and Immunology, 2023M. Sironi, D. Forni, J. C. de la Torre
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