Results 81 to 90 of about 2,648 (168)
Silver Nanoparticle‐Mediated Antiviral Efficacy against Enveloped Viruses: A Comprehensive Review
Global Challenges, Volume 9, Issue 5, May 2025.Silver nanoparticles (AgNPs) exhibit broad‐spectrum antiviral activity by targeting key viral structures and processes. They disrupt viral envelopes, compromising integrity, and bind to nucleocapsids, impairing viral replication. AgNPs also inhibit glycoprotein interactions, preventing viral attachment and entry into host cells.
Ekaterine Mosidze +8 more
wiley +1 more source
Review of Mammarenavirus Biology and Replication
Frontiers in Microbiology, 2018 The family Arenaviridae is divided into three genera: Mammarenavirus, Reptarenavirus, and Hartmanivirus. The Mammarenaviruses contain viruses responsible for causing human hemorrhagic fever diseases including New World viruses Junin, Machupo, Guanarito ...
Steven J. Hallam +3 more
doaj +1 more source
Viruses, 2018 New World arenaviruses cause fatal hemorrhagic disease in South America. Pirital virus (PIRV), a mammarenavirus hosted by Alston’s cotton rat (Sigmodon alstoni), causes a disease in Syrian golden hamsters (Mesocricetus auratus) (biosafety level-3 ...
Corey L. Campbell +7 more
doaj +1 more source
The Lassa Virus Stable Signal Peptide Undergoes a Conformational Change to Aid Viral Fusion
Chemistry – A European Journal, Volume 31, Issue 18, March 25, 2025.The unique stable signal peptide (SSP) of the Lassa virus glycoprotein complex undergoes a conformational change during pH‐dependent viral fusion. This revels a potential mechanism by which the enigmatic SSP influences the fusion process through interactions it makes with the fusion protein, glycoprotein 2 (GP2).
Shane D. Collins +3 more
wiley +1 more source
WIREs RNA, Volume 16, Issue 2, March/April 2025.Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus +3 more
wiley +1 more source
Frontiers in Immunology, 2019 The New World arenavirus Junin (JUNV) is the etiological agent of Argentine hemorrhagic fever (AHF). Previous studies of human macrophage infection by the Old-World arenaviruses Mopeia and Lassa showed that while the non-pathogenic Mopeia virus ...
María F. Ferrer +12 more
doaj +1 more source
Virology Journal, 2008 Background There is a significant requirement for the development and acquisition of reagents that will facilitate effective diagnosis, treatment, and prevention of Lassa fever.
Cashman Kathleen A +11 more
doaj +1 more source
CD164 is an endolysomal host factor for entry of Clade A New World Arenaviruses
Abstract Arenaviruses are divided into Old World (OW) and New World (NW) groups. OW arenaviruses enter cells through a pH-dependent receptor switch from a plasma-membrane factor to an endolysosomal receptor for subsequent membrane fusion, whereas clade B NW arenaviruses use transferrin receptor 1 without a secondary receptor.
Cassandra E. Thompson +11 more
openaire +1 more source
VirusesRubella is typically a mild viral illness, but it can lead to severe complications when contracted during pregnancy, such as pregnancy loss or developmental defects in the fetus (congenital rubella syndrome).
Lara I. Teodoro +6 more
doaj +1 more source