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Arenaviruses

2018
<p>The family Arenaviridae consists of over 30 members, some of which can infect humans and cause severe hemorrhagic fever. The three arenaviruses studied in this thesis, Machupo virus (MACV), Junín virus (JUNV), and Lassa virus (LASV), are causative agents of Bolivian hemorrhagic fever, Argentine hemorrhagic fever, and Lassa fever, respectively.
Rachel Bottjen Brouillette   +5 more
openaire   +1 more source

Arenaviruses

2017
Christopher J. Burrell   +2 more
openaire   +2 more sources

Biochemistry of Arenaviruses

1985
Although the isolation of lymphocytic choriomeningitis virus (LCMV), the prototype member of the arenavirus group, was initially reported by Armstrong and Lillie in 1934, the virus remained unclassified for many years because of the lack of information on its biochemical properties and morphology.
R W, Compans, D H, Bishop
openaire   +2 more sources

Tangeretin, an extract from Citrus peels, blocks cellular entry of arenaviruses that cause viral hemorrhagic fever.

Antiviral Research, 2018
The family Arenaviridae consists of numerous enveloped RNA viruses with ambisense coding strategies. Eight arenaviruses, including Lassa virus, are known to cause severe and fatal viral hemorrhagic fever (VHF) in humans, yet vaccines and treatments for ...
Ke Tang   +9 more
semanticscholar   +1 more source

Novel Insights into Cell Entry of Emerging Human Pathogenic Arenaviruses.

Journal of Molecular Biology, 2018
Viral hemorrhagic fevers caused by emerging RNA viruses of the Arenavirus family are among the most devastating human diseases. Climate change, global trade, and increasing urbanization promote the emergence and re-emergence of these human pathogenic ...
C. Fedeli, Hector Moreno, S. Kunz
semanticscholar   +1 more source

Arenaviruses

2011
There are few groups of viral zoonoses that have attracted such widespread publicity as the arenaviruses, particularly during the 1960’s and 1970’s when Lassa emerged as a major cause of haemorrhagic disease in West Africa. More than any other zoonoses, members of the family are used extensively for the study of virus-host relationships. Thus the study
openaire   +1 more source

Arenaviruses bite the “dust”

Blood, 2013
In this issue of Blood , Loria and colleagues present new aspects on the role of platelets in protecting against both lethal hemorrhagic diathesis and virus replication in viral hemorrhagic fever (VHF), using a murine model of lymphocytic choriomeningitis virus (LMCV) infection.[1][1] The ...
Ricardo M, Gómez, Mirta, Schattner
openaire   +2 more sources

Cleavage of the Glycoprotein of Arenaviruses

Activation of Viruses by Host Proteases, 2018
The arenaviruses are a large family of emerging negative-stranded RNA viruses that include several severe human pathogens causing hemorrhagic fevers with high mortality.
A. Pasquato, L. Cendron, S. Kunz
semanticscholar   +1 more source

Sequence Comparison Among Arenaviruses

1987
Contemporary techniques for DNA cloning and rapid nucleotide sequencing have made significant contributions to the present understanding of gene structure and regulation (see, for example, Gluzman and Shenk 1983; Gluzman 1985). Cloning has allowed the amplification of genetic material that may be difficult or impossible to propagate by conventional ...
P J, Southern, D H, Bishop
openaire   +2 more sources

Mammalian Reservoirs of Arenaviruses

2002
Arenaviruses are negative-stranded RNA viruses that have been isolated from several species of mammals in various parts of the world. With two exceptions, these viruses have all been isolated from rodents of the family Muridae — sensu Musser and Carleton (1993).
J, Salazar-Bravo   +2 more
openaire   +2 more sources

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