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Flipping out: role of arginine in hydrophobic interactions and biological formulation design. [PDF]

Chem Sci
Arginine has been a mainstay in biological formulation development for decades. To date, the way arginine modulates protein stability has been widely studied and debated. Here, we employed a hydrophobic polymer to decouple hydrophobic effects from other interactions relevant to protein folding.
Zajac JWP, Muralikrishnan P, Tohidian I, Zeng X, Heldt CL, Perry SL, Sarupria S.   +6 more
europepmc   +2 more sources

Nitrogen utilization analysis reveals the synergetic effect of arginine and urea in promoting fucoxanthin biosynthesis in the mixotrophic marine diatom Phaeodactylum tricornutum

Frontiers in Marine Science, 2022
Fucoxanthin is a new dietary ingredient applied in healthy foods with specific benefits of body weight loss and liver fat reduction. The marine diatom Phaeodactylum tricornutum is a highly suitable species for fucoxanthin production. In the present study,
Runqing Yang, Dong Wei, Georg Pohnert
doaj   +1 more source

Synechocystis sp. PCC 6803 Requires the Bidirectional Hydrogenase to Metabolize Glucose and Arginine Under Oxic Conditions

Frontiers in Microbiology, 2022
The cyanobacterium Synechocystis sp.PCC 6803 possesses a bidirectional NiFe-hydrogenase, HoxEFUYH. It functions to produce hydrogen under dark, fermentative conditions and photoproduces hydrogen when dark-adapted cells are illuminated.
Heinrich Burgstaller, Yingying Wang, Johanna Caliebe, Johanna Caliebe, Vanessa Hueren, Jens Appel, Jens Appel, Marko Boehm, Marko Boehm, Sinje Leitzke, Marius Theune, Marius Theune, Paul W. King, Kirstin Gutekunst, Kirstin Gutekunst   +14 more
doaj   +1 more source

Arginine Regulates Zygotic Genome Activation in Porcine Embryos Under Nutrition Restriction

Frontiers in Veterinary Science, 2022
Arginine has a positive effect on pre-implantation development in pigs. However, the exact mechanism by which arginine promotes embryonic development is undefined.
Tianrui Zhang, Yingying Zheng, Tianya Kuang, Lianyu Yang, Hailong Jiang, Heming Wang, Heming Wang, Yicheng Zhao, Rui Han, Dongsheng Che   +9 more
doaj   +1 more source

Arginine-dependent immune responses

Cellular and Molecular Life Sciences, 2021
A growing body of evidence indicates that, over the course of evolution of the immune system, arginine has been selected as a node for the regulation of immune responses.
Adrià-Arnau Martí i Líndez, W. Reith
semanticscholar   +1 more source

Hydrophobicity of arginine leads to reentrant liquid-liquid phase separation behaviors of arginine-rich proteins

Nature Communications, 2022
Intrinsically disordered proteins rich in cationic amino acid groups can undergo Liquid-Liquid Phase Separation (LLPS) in the presence of charge-balancing anionic counterparts.
Yu Hong, Saeed Najafi, Thomas Casey, J. Shea, Song-I Han, D. Hwang   +5 more
semanticscholar   +1 more source

Research progress on natural antibacterial ingredients of glass ionomer cement

口腔疾病防治, 2022
Glass ionomer cement (GIC) is widely used as a common filling material in dentistry but still exhibits problems with secondary caries and fractures. Thus, the antibacterial and anti-caries performance of GIC needs to be further improved. In recent years,
ZHANG Yishuang, TAO Dihao, GUO Andi, ZHENG Hao, WANG Suping   +4 more
doaj   +1 more source

Association between serum arginine levels and cancer risk: A community-based nested case-control study

Frontiers in Nutrition, 2022
ObjectiveThe effect of arginine on tumors appears to be bidirectional. The association of serum arginine with the risk of incident cancer remains uncovered at present.
Tong Liu, Tong Liu, Tong Liu, Xiaomeng Wang, Pingping Jia, Pingping Jia, Pingping Jia, Chenan Liu, Chenan Liu, Chenan Liu, Yaping Wei, Yun Song, Shuqun Li, Lishun Liu, Binyan Wang, Hanping Shi, Hanping Shi, Hanping Shi   +17 more
doaj   +1 more source

Arginine Signaling and Cancer Metabolism

Cancers, 2021
Simple Summary In this review, we describe arginine’s role as a signaling metabolite, epigenetic regulator and mitochondrial modulator in cancer cells, and summarize recent progress in the application of arginine deprivation as a cancer therapy. Abstract
Chia-Lin Chen, S. Hsu, David Ann, Y. Yen, H. Kung   +4 more
semanticscholar   +1 more source

Analyses of the Effects of Arginine, Nicotine, Serotype and Collagen-Binding Proteins on Biofilm Development by 33 Strains of Streptococcus mutans

Frontiers in Oral Health, 2021
Streptococcus mutans serotype k strains comprise <3% of oral isolates of S. mutans but are prominent in diseased cardiovascular (CV) tissue. Collagen binding protein (CBP) genes, cbm and cnm, are prevalent in serotype k strains and are associated with
Dawn R. Wagenknecht, Richard L. Gregory
doaj   +1 more source