Results 31 to 40 of about 793,177 (388)

Animal source foods, rich in essential amino acids, are important for linear growth and development of young children in low‐ and middle‐income countries

Maternal and Child Nutrition, 2022
Growth faltering under 5 years of age is unacceptably high worldwide, and even more children, while not stunted, fail to reach their growth potential. The time between conception and 2 years of age is critical for development.
Panam Parikh, Richard Semba, Mark Manary, Sumathi Swaminathan, Emorn Udomkesmalee, Rolf Bos, Bee Koon Poh, Nipa Rojroongwasinkul, Jan Geurts, Rini Sekartini, Tran Thuy Nga   +10 more
doaj   +1 more source

The Role of Amino Acids in the Crosstalk Between Mesenchymal Stromal Cells and Neoplastic Cells in the Hematopoietic Niche

Frontiers in Cell and Developmental Biology, 2021
Within the bone marrow hematopoietic cells are in close connection with mesenchymal stromal cells (MSCs), which influence the behavior and differentiation of normal or malignant lymphoid and myeloid cells. Altered cell metabolism is a hallmark of cancer,
Martina Chiu, Giuseppe Taurino, Massimiliano G. Bianchi, Ovidio Bussolati   +3 more
doaj   +1 more source

Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity.

Blood, 2020
Haematological and solid cancers catabolise the semi-essential amino acid arginine to drive cell proliferation. However, the resulting low arginine microenvironment also impairs chimeric antigen receptor T cells (CAR-T) cell proliferation, limiting their
Livingstone Fultang, S. Booth, Orli Yogev, Barbara Martins Da Costa, Vanessa Tubb, Silvia Panetti, Victoria Stavrou, Ugo Scarpa, A. Jankevics, Gavin R. Lloyd, A. Southam, Steven P Lee, W. Dunn, L. Chesler, F. Mussai, Carmela De Santo   +15 more
semanticscholar   +1 more source

Protocol to assess the tolerogenic properties of adoptively transferred dendritic cells during murine experimental autoimmune encephalomyelitis

STAR Protocols, 2022
Summary: By their capacity to induce peripheral T cell tolerance, dendritic cells (DCs) present a promising target cell and therapeutic strategy for treatment of several autoimmune diseases including multiple sclerosis (MS).
Andrea Vogel, Martina Kerndl, Gernot Schabbauer, Omar Sharif   +3 more
doaj  

Dietary Arginine Regulates Severity of Experimental Colitis and Affects the Colonic Microbiome

Frontiers in Cellular and Infection Microbiology, 2019
There is great interest in safe and effective alternative therapies that could benefit patients with inflammatory bowel diseases (IBD). L-arginine (Arg) is a semi-essential amino acid with a variety of physiological effects.
Kshipra Singh, Kshipra Singh, Alain P. Gobert, Alain P. Gobert, Lori A. Coburn, Lori A. Coburn, Lori A. Coburn, Daniel P. Barry, Margaret Allaman, Mohammad Asim, Paula B. Luis, Paula B. Luis, Claus Schneider, Claus Schneider, Claus Schneider, Ginger L. Milne, Helen H. Boone, Meghan H. Shilts, M. Kay Washington, Suman R. Das, Suman R. Das, M. Blanca Piazuelo, Keith T. Wilson, Keith T. Wilson, Keith T. Wilson, Keith T. Wilson   +25 more
doaj   +1 more source

Nitric Oxide Deficiency in Mitochondrial Disorders: The Utility of Arginine and Citrulline

Frontiers in Molecular Neuroscience, 2021
Mitochondrial diseases represent a growing list of clinically heterogeneous disorders that are associated with dysfunctional mitochondria and multisystemic manifestations.
Mohammed Almannai, Mohammed Almannai, Ayman W. El-Hattab, Ayman W. El-Hattab   +3 more
doaj   +1 more source

European Sea Bass (Dicentrarchus labrax) immune status and disease resistance are impaired by arginine dietary supplementation [PDF]

, 2015
Infectious diseases and fish feeds management are probably the major expenses in the aquaculture business. Hence, it is a priority to define sustainable strategies which simultaneously avoid therapeutic procedures and reinforce fish immunity.
A Nomura, AE Toranzo, Aires Oliva-Teles, AK Sikalidis, Ariadna Sitjà-Bobadilla, B Costas, B Fouz, Belén Fouz, Benjamín Costas, C Bogdan, C Breuillard, C Pohlenz, C Prolo, C Uribe, Cláudia Aragão, CM Wood, DA Plouffe, Daniel Merrifield, E Ringo, G Chen, H Kleinert, HZ Lin, I Frans, J Jiang, JA Buentello, Jaume Pérez-Sánchez, JHWM Rombout, JM Lawler, JS Ballantyne, JZ Tan, K Kapp, K Zhao, KM Leland, L Tang, Lluis Tort, M Galeottia, M Machado, MP Sepulcre, N Nakaya, N Tejera, P Li, P Li, PJ Popovic, QC Zhou, Rita Azeredo, S Graham, S Nikoskelainen, S Rengpipat, S Srivastava, SJ Kaushik, SM Andersen, T Hanada, T Lawrence, TJ Ahmed, V Bronte, Y Chen, ZY Cheng, ZY Cheng   +57 more
core   +5 more sources

Arginase from kiwifruit: properties and seasonal variation [PDF]

, 1988
The in vitro activity of arginase (EC 3.5.3.1) was investigated in youngest-mature leaves and roots (1-3 mm diameter) of kiwifruit vines (Actinidia deliciosa var. deliciosa) during an annual growth cycle, and enzyme from root material partially purified.
Dwek, RA, Fellows, LE, Fleet, GW, Karpas, A, Namgoong, SK, Petursson, S, Ramsden, NG, Smith, PW, Son, JC, Tyms, AS   +9 more
core   +4 more sources

Obese women on a low energy rice and bean diet: effects of leucine, arginine or glycine supplementation on protein turnover

Brazilian Journal of Medical and Biological Research, 2001
This study examined if leucine, arginine or glycine supplementation in adult obese patients (body mass index of 33 ± 4 kg/m²) consuming a Brazilian low energy and protein diet (4.2 MJ/day and 0.6 g protein/kg) affects protein and amino acid metabolism ...
J.S. Marchini, C.R. Lambertini, E. Ferriolli, J.E. Dutra de Oliveira   +3 more
doaj   +1 more source

L-arginine: A unique amino acid for improving depressed wound immune function following hemorrhage [PDF]

, 2002
Objective: To determine whether L-arginine has any salutary effects on wound immune cell function following trauma-hemorrhage. Background. Depressed wound immune function contributes to an increased incidence of wound infections following hemorrhage ...
Angele, Martin K., Angele, Peter, Chaudry, Irshad H., Hatz, Rudolf A., Hernandez-Richter, Thomas, Nitsch, Stefan M., Schildberg, Friedrich Wilhelm, Wichmann, Mathias W.   +7 more
core   +1 more source