Results 31 to 40 of about 753,681 (356)

Targeting Immunometabolism in Glioblastoma

open access: yesFrontiers in Oncology, 2021
We have only recently begun to understand how cancer metabolism affects antitumor responses and immunotherapy outcomes. Certain immunometabolic targets have been actively pursued in other tumor types, however, glioblastoma research has been slow to ...
Aditya A. Mohan   +8 more
doaj   +1 more source

Arginine and Endothelial Function

open access: yesBiomedicines, 2020
Arginine (L-arginine), is an amino acid involved in a number of biological processes, including the biosynthesis of proteins, host immune response, urea cycle, and nitric oxide production.
J. Gambardella   +5 more
semanticscholar   +1 more source

Chemical and Metabolic Aspects of Antimetabolite Toxins Produced by Pseudomonas syringae Pathovars

open access: yesToxins, 2011
Pseudomonas syringae is a phytopathogenic bacterium present in a wide variety of host plants where it causes diseases with economic impact. The symptoms produced by Pseudomonas syringae include chlorosis and necrosis of plant tissues, which are caused ...
Eva Arrebola   +3 more
doaj   +1 more source

NMR Dynamics Investigation of Ligand-Induced Changes of Main and Side-Chain Arginine N-H’s in Human Phosphomevalonate Kinase [PDF]

open access: yes, 2010
Phosphomevalonate kinase (PMK) catalyzes phosphoryl transfer from adenosine triphosphate (ATP) to mevalonate 5-phosphate (M5P) on the pathway for synthesizing cholesterol and other isoprenoids.
Cai, Sheng   +4 more
core   +2 more sources

Arginine metabolism: nitric oxide and beyond.

open access: yesBiochemical Journal, 1998
Arginine is one of the most versatile amino acids in animal cells, serving as a precursor for the synthesis not only of proteins but also of nitric oxide, urea, polyamines, proline, glutamate, creatine and agmatine.
Guoyao Wu, S. Morris
semanticscholar   +1 more source

Arginine Promotes the Expression of Aquaporin-3 and Water Transport in Porcine Trophectoderm Cells Through NO- and cAMP-Dependent Mechanisms

open access: yesFrontiers in Bioscience-Landmark, 2022
Background: Dietary supplementation with L-arginine (Arg) has been shown to increase the volume of fetal fluids in gestating swine. Aquaporins (AQPs), known as water channel proteins, are essential for embryonic growth and development.
Cui Zhu   +8 more
doaj   +1 more source

Arginine, a Key Residue for the Enhancing Ability of an Antifreeze Protein of the Beetle Dendroides canadensis [PDF]

open access: yes, 2009
Antifreeze proteins (AFPs) can produce a difference between the nonequilibrium freezing point and the melting point, termed thermal hysteresis (TH). The TH activity of an antifreeze protein (AFP) depends on the specific AFP and its concentration as well ...
Amornwittawat, Natapol   +7 more
core   +2 more sources

Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity.

open access: yesBlood, 2020
Haematological and solid cancers catabolise the semi-essential amino acid arginine to drive cell proliferation. However, the resulting low arginine microenvironment also impairs chimeric antigen receptor T cells (CAR-T) cell proliferation, limiting their
Livingstone Fultang   +15 more
semanticscholar   +1 more source

Estimation of genetic parameters for egg production traits in Japanese quail that selected for immune responses and fed different level of dietary L-arginine [PDF]

open access: yesمجلة جامعة كركوك للعلوم الزراعية, 2023
This study was conducted in the fields of the Department of Animal Production - College of Agriculture at Kirkuk University for the period from 6/14/2021 to 7/30/2022.
Ahmed Shaker   +2 more
doaj   +1 more source

Protocol to assess the tolerogenic properties of adoptively transferred dendritic cells during murine experimental autoimmune encephalomyelitis

open access: yesSTAR Protocols, 2022
Summary: By their capacity to induce peripheral T cell tolerance, dendritic cells (DCs) present a promising target cell and therapeutic strategy for treatment of several autoimmune diseases including multiple sclerosis (MS).
Andrea Vogel   +3 more
doaj  

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