Blood, 2020 Haematological and solid cancers catabolise the semi-essential amino acid arginine to drive cell proliferation. However, the resulting low arginine microenvironment also impairs chimeric antigen receptor T cells (CAR-T) cell proliferation, limiting their
Livingstone Fultang +15 more
semanticscholar +1 more source
Arginine, a Key Residue for the Enhancing Ability of an Antifreeze Protein of the Beetle Dendroides canadensis [PDF]
, 2009 Antifreeze proteins (AFPs) can produce a difference between the nonequilibrium freezing point and the melting point, termed thermal hysteresis (TH). The TH activity of an antifreeze protein (AFP) depends on the specific AFP and its concentration as well ...
Amornwittawat, Natapol +7 more
core +2 more sources
STAR Protocols, 2022 Summary: By their capacity to induce peripheral TÂ cell tolerance, dendritic cells (DCs) present a promising target cell and therapeutic strategy for treatment of several autoimmune diseases including multiple sclerosis (MS).
Andrea Vogel +3 more
doaj
L-arginine: A unique amino acid for improving depressed wound immune function following hemorrhage [PDF]
, 2002 Objective: To determine whether L-arginine has any salutary effects on wound immune cell function following trauma-hemorrhage. Background. Depressed wound immune function contributes to an increased incidence of wound infections following hemorrhage ...
Angele, Martin K. +7 more
core +1 more source
Arginase from kiwifruit: properties and seasonal variation [PDF]
, 1988 The in vitro activity of arginase (EC 3.5.3.1) was investigated in youngest-mature leaves and roots (1-3 mm diameter) of kiwifruit vines (Actinidia deliciosa var. deliciosa) during an annual growth cycle, and enzyme from root material partially purified.
Dwek, RA +9 more
core +4 more sources
Long-term supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine for pressure ulcer in sedentary older adults: a retrospective matched case-control study [PDF]
Journal of Yeungnam Medical Science, 2023 Background Growing evidence suggests that beta-hydroxy-beta-methylbutyrate (HMB), arginine (Arg), and glutamine (Gln) positively affect wound recovery. This study investigated the effects of long-term administration of HMB/Arg/Gln on pressure ulcer (PU ...
Igor Kisil, Yuri Gimelfarb
doaj +1 more source
The Ergogenic Potential of Arginine [PDF]
Journal of the International Society of Sports Nutrition, 2004 Arginine is a conditionally essential amino acid that is involved in protein synthesis, the detoxification of ammonia, and its conversion to glucose as well as being catabolized to produce energy. In addition to these physiological functions, arginine has been purported to have ergogenic potential. Athletes have taken arginine for three main reasons: 1)
Bill Campbell +2 more
openaire +3 more sources
Splanchnic metabolism of nutrients and hormones in steers fed alfalfa under conditions of increased absorption of ammonia and L-arginine supply across the portal-drained viscera [PDF]
, 2005 Effects of increased ammonia and/or arginine absorption on net splanchnic (portal-drained viscera [PDV] plus liver) metabolism of nonnitrogenous nutrients and hormones in cattle were examined.
Assan +42 more
core +1 more source
Plasmatic Dimethylarginines in Dogs With Myxomatous Mitral Valve Disease
Frontiers in Veterinary Science, 2021 Plasmatic dimethylarginines, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) are considered biomarkers of endothelial and renal dysfunction, respectively, in humans.
Carlotta Valente +7 more
doaj +1 more source
Arginine deprivation: a potential therapeutic for cancer cell metastasis? A review
Cancer Cell International, 2020 Arginine is a semi essential amino acid that is used in protein biosynthesis. It can be obtained from daily food intake or synthesized in the body through the urea cycle using l -citrulline as a substrate.
Houssam Al-Koussa +4 more
semanticscholar +1 more source