Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Plant-mycorrhizal fungi interaction and response to inoculation with different growth-promoting fungi [PDF]
: The symbiotic interaction between arbuscular mycorrhizal fungi (AMF) and 70-90% of the plant species is largely studied, but ectomycorrhizal fungi, Piriformospora indica, Trichoderma sp., and dark septate endophytes (DSE), also establish beneficial ...
Carlos Vergara +6 more
doaj +3 more sources
Nitric Oxide Deficiency in Mitochondrial Disorders: The Utility of Arginine and Citrulline
Mitochondrial diseases represent a growing list of clinically heterogeneous disorders that are associated with dysfunctional mitochondria and multisystemic manifestations.
Mohammed Almannai +3 more
doaj +1 more source
Biochemical regulation of arginine biosynthesis in plants [PDF]
Arginine plays a relevant role in plant metabolism due to its importance as building block of proteins but also as precursor of multiple secondary metabolites, polyamines and nitric oxide.
Canovas-Ramos, Francisco Miguel +4 more
core
Translating Metabolic Reprogramming into New Targets for Kidney Cancer. [PDF]
In the age of bioinformatics and with the advent of high-powered computation over the past decade or so the landscape of biomedical research has become radically altered.
Abu Aboud, Omran, Weiss, Robert H
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Identification of Loci and Candidate Genes Associated with Arginine Content in Soybean
Soybean (Glycine max) seeds are rich in amino acids, offering key nutritional and physiological benefits. In this study, 290 soybean accessions from the USDA Germplasm Collection based in Urbana, IL Information Network (GRIN) were analyzed.
Jiahao Ma +10 more
doaj +1 more source
COVID-19 ranges from asymptomatic in 35% of cases to severe in 20% of patients. Differences in the type and degree of inflammation appear to determine the severity of the disease.
Matthew J. Dean +32 more
doaj +1 more source
ArgR is an essential local transcriptional regulator of the arcABC-operon in Streptococcus suis and crucial for biological fitness in acidic environment [PDF]
Streptococcus suis is one of the most important pathogens in pigs and can also cause severe infections in humans. Despite its clinical relevance very little is known about the factors contributing to its virulence.
Benga, L. +6 more
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

