Results 51 to 60 of about 784,368 (407)
Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis [PDF]
American Journal of Physiology-Renal Physiology, 2018 Research into metabolic reprogramming in cancer has become commonplace, yet this area of research has only recently come of age in nephrology. In light of the parallels between cancer and autosomal dominant polycystic kidney disease (ADPKD), the latter is currently being studied as a metabolic disease.
Trott, Josephine F +11 more
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The Journal of Nutrition, 2004 Arginine is a dibasic, cationic, semiessential amino acid with numerous roles in cellular metabolism. It serves as an intermediate in the urea cycle and as a precursor for protein, polyamine, creatine and nitric oxide (NO) biosynthesis. Arginine is conditionally essential since it becomes necessary under periods of growth and after recovery after ...
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Plasma arginine vasopressin concentrations in epileptics under monotherapy [PDF]
, 1983 Plasma arginine vasopressin concentrations were determined by radio-immunoassay in 112 adult epileptics who were taking carbamazepine, phenytoin, primidone, or sodium valproate in long-term monotherapy, and in 19 controls.
E Perucca +15 more
core +1 more source
Refolding Technology for scFv Using a New Detergent, N-Lauroyl-L-glutamate and Arginine
Antibodies, 2012 Monoclonal antibodies to the soluble antigens or cell surface markers hold great promise as effective human therapeutics. One of the major disadvantages is its large size, which prevents efficient penetration into the target tissues.
Tsutomu Arakawa +2 more
doaj +1 more source
Comparative Density Functional Theory and Density Functional Tight Binding Study of Arginine and Arginine-Rich Cell-Penetrating Peptide TAT Adsorption on Anatase TiO2 [PDF]
Phys. Chem. Chem. Phys., 18, 19902-19917 (2016), 2016 We present a comparative Density Functional Theory (DFT) and Density Functional Tight Binding (DFTB) study of geometries and electronic structures of arginine (Arg), arginine adsorbed on the anatase (101) surface of titania in several adsorption configurations, and of an arginine-rich cell penetrating peptide TAT and its adsorption on the surface of ...
arxiv +1 more source
Folia Pharmacologica Japonica, 2002 L-Arginine has attracted major interest because it has been identified as the natural substrate of nitric oxide synthase and is now recognized as a major player in the regulation of biological function. The arginine paradox refers to the phenomenon that exogenous L-arginine causes NO-mediated biological effects despite the fact that nitric oxide ...
Toshio Nakaki, Keiichi Hishikawa
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Arginine and nitrogen storage [PDF]
Current Opinion in Structural Biology, 2008 When nitrogen is abundant, prokaryotic and eukaryotic oxygen-producing photosynthetic organisms store nitrogen as arginine, by relieving feedback inhibition of the arginine biosynthesis controlling enzyme, N-acetylglutamate kinase (NAGK). The signalling protein PII, an ancient and widely distributed nitrogen/carbon/ADP/ATP sensor, mediates feedback ...
Llácer, José Luis +2 more
openaire +4 more sources
Frontiers in Immunology, 2021 COVID-19 ranges from asymptomatic in 35% of cases to severe in 20% of patients. Differences in the type and degree of inflammation appear to determine the severity of the disease.
Matthew J. Dean +32 more
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Hyaluronan-Arginine Enhanced Interaction Emerges from Distinctive Molecular Signature with Improved Electrostatics and Side-Chain Specificity [PDF]
arXiv, 2023 Hyaluronan, a sugar polymer found outside the plasma membrane, is a critical component of the extracellular matrix (ECM) scaffold. Hyaluronan's length and moderate negative charge aid in ECM entanglement and solubility. This allows it to effectively foster gel-like conditions, which are critical for supporting and protecting cells in various tissues ...
arxiv
Arginine-enriched mixed-charge domains provide cohesion for nuclear speckle condensation
bioRxiv, 2019 Low-complexity protein domains promote the formation of various biomolecular condensates. However, in many cases, the precise sequence features governing condensate formation and identity remain unclear.
Jamie A. Greig +6 more
semanticscholar +1 more source