Results 31 to 40 of about 18,348 (185)

Synthesis of Novel Arginine Building Blocks with Increased Lipophilicity Compatible with Solid-Phase Peptide Synthesis

Molecules, 2023
Arginine, due to the guanidine moiety, increases peptides’ hydrophilicity and enables interactions with charged molecules, but at the same time, its presence in a peptide chain might reduce its permeability through biological membranes.
Mladena Glavaš, Agata Gitlin-Domagalska, Natalia Ptaszyńska, Dominika Starego, Sylwia Freza, Dawid Dębowski, Aleksandra Helbik-Maciejewska, Anna Łęgowska, Chaim Gilon, Krzysztof Rolka   +9 more
doaj   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

iNew Medicine, EarlyView.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang, Yinbo Xu, Yiting Zhao, Liuyi Li, Zhengyi Cheng, Zhongqi Zhang, Yuhang Luo, Qiaoling Liu, Chen Gong, Shichun Shen   +9 more
wiley   +1 more source

Age and Nocturnal Polyuria in Nocturia: A Multicenter Voiding Diary Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Although the prevalence of nocturnal polyuria (NP) increases with age, the mechanisms underlying age‐related changes in voiding patterns and the daytime–nighttime distribution of urine volume remain unclear. Given that the severity of nocturia and bladder function may differ across age groups, age‐specific voiding profiles require
Kota Kawase, Yoshinori Nishino, Kanako Matsuoka, Shunta Makabe, Ryo Tanji, Hiroki Hoshino, Kei Kawada, Kousei Miwa, Masayuki Tomioka, Tomoki Taniguchi, Koji Iinuma, Yuki Tobisawa, Keita Nakane, Yoshiyuki Kojima, Takahiko Mitsui, Takuya Koie   +15 more
wiley   +1 more source

Adipsic central diabetes insipidus as a result of neurosarcoidosis

Revista Mexicana de Endocrinología, Metabolismo y Nutrición
Sarcoidosis is a systemic multisystem inflammatory disorder of unknown etiology characterized by the presence of non-caseating granulomas. Neurosarcoidosis leads to hypothalamus- pituitary axis dysfunction, and the most common clinical manifestation is ...
Radmila Milosheska, Ivana Mickovski, Daniela Buklioska Ilijevska   +2 more
doaj   +1 more source

Estimation the activity of Copeptin, insulin, and C-peptide from patients with polycystic ovary syndrome

Tikrit Journal of Pure Science, 2018
Copeptin, the C-terminal part of the vasopressin prohormone, is secreted stoichiometrically with vasopressin that is more easily measured than Arginine vasopressin.
Entedhar R. Sarhat, Madlen Qassm Abbas
doaj   +1 more source

Histiocytosis development and clinical variation through the lens of genomics

The Journal of Pathology, EarlyView.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps, Astrid GS van Halteren, Tom van Wezel, Pancras CW Hogendoorn   +3 more
wiley   +1 more source

Maternal glucocorticoids have persistent effects on offspring social phenotype irrespective of opportunity for social buffering

Journal of Animal Ecology, EarlyView.
This study tests whether early‐life maternal association buffers offspring from the effects of prenatal stress in a facultatively social lizard. Despite clear effects of maternal glucocorticoids on growth and social behaviour, social associations did not mitigate these effects, revealing limits to social buffering in this species.
Kirsty J. MacLeod, Alix Bouffet‐Halle, Erik Wapstra, Tobias Uller, Geoffrey M. While   +4 more
wiley   +1 more source

Strategies for discontinuing vasopressin and norepinephrine during the recovery phase of shock: a single-center retrospective study

Journal of Intensive Care
Background The optimal strategy for discontinuing arginine vasopressin and norepinephrine in patients recovering from shock remains uncertain. Although prior studies have suggested a higher risk of hypotension when arginine vasopressin is discontinued ...
Shiho Suganuma, Shigehiko Uchino, Seiya Nishiyama, Yusuke Sasabuchi, Shinshu Katayama   +4 more
doaj   +1 more source

Use of 'Vaptans' in treatment of hyponatremia

Türk Kardiyoloji Derneği Arşivi, 2015
Hyponatremia is the most prevalent electrolyte imbalance, and may be present in up to 30% of hospitalized patients. It is an important predictor of in-hospital mortality.
Aslı Tanındı, Hasan Fehmi Töre
doaj   +1 more source

Pufferfish exposure and presumed tetrodotoxicosis in Australian dogs: 372 cases (2007–2018)

Australian Veterinary Journal, EarlyView.
Introduction Tetrodotoxin (TTX) is a neurotoxin found in pufferfish that results in the blockade of excitatory conduction and clinical signs including gastrointestinal upset and paralysis. The objectives of this study were to describe the epidemiology of pufferfish exposure and presumed tetrodotoxicosis in dogs, and to determine associations with the ...
J Hanson, CR Sharp, EM Leister
wiley   +1 more source