Results 81 to 90 of about 27,759 (158)

Primers used for qPCR.

, 2014
CPS1, carbamoyl phosphate synthetase 1; OTC, ornithine carbamoyltransferase; ASS1, argininosuccinate synthetase; ASL, argininosuccinate lyase; ARG1, arginase; NAGS, N-acetylglutamate synthase; GLUL, glutamate–ammonia ligase; GLUD1, glutamate ...
Giora van Straten (580550), Frank C. P. Holstege (117137), Robert P. Favier (144780), Marian J. A. Groot Koerkamp (117136), Frank G. van Steenbeek (194928), Hille Fieten (144796), Ingrid H. van Gils (580551), Guy C. M. Grinwis (165277), Bart Spee (66184), Jan Rothuizen (66188), Anne Kummeling (381713)   +10 more
core   +1 more source

Biocatalytic asymmetric Michael addition reaction ofl-arginine to fumarate for the green synthesis of N-(([(4S)-4-amino-4-carboxy-butyl]amino)iminomethyl)-l-aspartic acid lithium salt (l-argininosuccinic acid lithium salt)

, 2017
The biocatalytic asymmetric Michael addition ofl-arginine to fumarate using argininosuccinate lyase (ASL) has enabled the synthesis of the key metabolitel-argininosuccinic acid lithium salt1for the first time, with excellent yield and purity.
A. Wszolek, H. Brundiek, R. Wohlgemuth, M. Obkircher, R. Meier, B. Schoenenberger   +5 more
core   +1 more source

Protein Kinase Cα Phosphorylates a Novel Argininosuccinate Synthase Site at Serine 328 during Calcium-dependent Stimulation of Endothelial Nitric-oxide Synthase in Vascular Endothelial Cells [PDF]

, 2012
Endothelial nitric-oxide synthase (eNOS) utilizes l-arginine as its principal substrate, converting it to l-citrulline and nitric oxide (NO). l-Citrulline is recycled to l-arginine by two enzymes, argininosuccinate synthase (AS) and argininosuccinate ...
Corbin, Karen D., Pendleton, Laura C., Eichler, Duane C., Haines, Ricci J.   +3 more
core   +1 more source

Nitric oxide is required for lung alveolarization revealed by deficiency of argininosuccinate lyase. [PDF]

Hum Mol Genet, 2023
Jin Z, Jiang MM, Lee B.
europepmc   +1 more source

Arabidopsis thaliana argininosuccinate lyase structure uncovers the role of serine as the catalytic base

Arginine is an important amino acid in plants, as it not only plays a structural role and serves as nitrogen storage but is also a precursor for various molecules, including polyamines and proline.
Nielipinski, Maciej, Pietrzyk-Brzezinska, Agnieszka J., Sekula, Bartosz, Nielipinska, Dominika   +3 more
core   +1 more source

Sustained engraftment and tissue enzyme activity after liver cell transplantation for argininosuccinate lyase deficiency.

, 2006
BACKGROUND & AIMS: Donor cell engraftment with expression of enzyme activity is the goal of liver cell transplantation for inborn errors of liver metabolism with a view to achieving sustained metabolic control.
Stéphenne, Xavier, Najimi, Mustapha, Nassogne, Marie-Cécile, Smets, Françoise, Sibille, Catherine, Sokal, Etienne   +5 more
core   +1 more source

Structure of human argininosuccinate synthetase

, 2008
Argininosuccinate synthetase catalyzes the transformation of citrulline and aspartate into argininosuccinate and pyrophos­phate using the hydrolysis of ATP to AMP and pyrophos­phate.
Karlberg, T., van den Berg, S., Flores, A., Hammarstrom, M., Collins, R., Uppenberg, J., Holmberg Schiavone, L., Hogbom, M., Karlberg, T,, Flores, A, Schiavone, LH, Collins, R,, Hammarstrom, M, Hogbom, M, van, den Berg S,, Uppenberg, J   +15 more
core   +2 more sources

Sequence analysis of the ARG7 gene of Schizosaccharomyces pombe coding for argininosuccinate lyase. Expression of the gene in Saccharomyces cerevisiae. [PDF]

, 1991
peer reviewedThe complete nucleotide sequence of the ARG7 gene, coding for argininosuccinate lyase (EC 4.3.2.1), in the fission yeast (Schizosaccharomyces pombe) has been determined. It consists of an open reading frame of 461 codons. The deduced protein
Loppes, Roland, Joris, Bernard, Michels, R, Decroupette, I   +3 more
core   +1 more source

Model of reciprocal regulation of arginase 1 (ARG1) and nitric oxide synthase 2 (NOS2).

, 2015
Downstream metabolic products (blue framed) and their association with components of inflammatory responses (red). Enzymes (blue ellipses), NOHA: N-hydroxyarginine, OAT: ornithine aminotransferase, ODC: ornithine decarboxylase, ACL: argininosuccinate ...
Frieder Hadlich (732945), Wiebke Demasius (790105), Rosemarie Weikard (82446), Christa Kühn (790106)   +3 more
core   +1 more source

Bacterial expression of mutant argininosuccinate lyase reveals imperfect correlation of in-vitro enzyme activity with clinical phenotype in argininosuccinic aciduria [PDF]

, 2011
BACKGROUND: The urea cycle defect argininosuccinate lyase (ASL) deficiency has a large spectrum of presentations from highly severe to asymptomatic. Enzyme activity assays in red blood cells or fibroblasts, although diagnostic of the deficiency, fail to ...
Murielle Groux, Engel, Katharina, Eggimann, Sandra, Christoph Berning, Katharina Engel, Groux, Murielle, Berning, Christoph, Mercimek-Mahmutoglu, Saadet, Sandra Eggimann, Vuissoz, Jean-Marc, Liyan Hu, Klaus, Vera, Hu, Liyan, Vera Klaus, Häberle, Johannes, Sylvia Stöckler, Dorothea Moeslinger, Moeslinger, Dorothea, Johannes Häberle, Stöckler, Sylvia, Jean‐Marc Nuoffer, Nuoffer, Jean-Marc, Jean‐Marc Vuissoz, Bendicht Wermuth, Saadet Mercimek‐Mahmutoglu, Wermuth, Bendicht   +25 more
core   +2 more sources