Results 71 to 80 of about 27,759 (158)

Fatal consequences of limited health literacy in a patient with a rare metabolic disease

Molecular Genetics and Metabolism Reports
A Black young adult female diagnosed with argininosuccinate lyase deficiency at 6 months of age encountered significant barriers to care for the first 16 years of her life due to socioeconomic factors and parental neglect.
Markey C. McNutt
doaj   +1 more source

Amino Acid and Lipid Metabolism in Cancer: Mechanisms and Therapeutic Opportunities

MedComm, Volume 7, Issue 8, August 2026.
Amino Acid and lipid metabolism in cancer: (A) Regulation of Amino acid transportation and metabolism in cancer. (B) The core organization of lipid metabolic reprogramming in cancer and their functional consequences. ABSTRACT Metabolic reprogramming is a defining feature of cancer and a major contributor to immune escape.
Zixu Wang, Xin Fu, Jingchao Bai, Yanguo Liu, Kai Huang   +4 more
wiley   +1 more source

Ornithine cycle in Nostoc PCC 73102: Presence of an in vitro functional argininosuccinate lyase

, 1997
The presence of argininosuccinate lyase (ASL), an enzyme catalyzing the final step of arginine biosynthesis, was demonstrated in the heterocystous cyanobacterium Nostoc PCC 73102 by measuring in vitro enzyme activity and by visualization of ASL in ...
Lindblad, P,, Jansson, E,, Troshina, O,
core  

Ammonia Metabolism in the Aging Liver: Emerging Mechanistic Insights

Aging Cell, Volume 25, Issue 8, August 2026.
Liver aging may weaken ammonia‐detoxification reserve by disrupting mitochondrial ureagenesis, GS‐mediated scavenging, glutamine metabolism, and metabolic zonation. This emerging framework links impaired nitrogen handling to potential hepatic stress amplification and systemic crosstalk, while highlighting the need for direct validation in physiological
Heng Zhang, Guangyu Liang, Anding Liu
wiley   +1 more source

The Swedish National Pediatric Cataract Register (PECARE): Coexisting systemic disorders 2007–2023

Acta Ophthalmologica, Volume 104, Issue 5, Page 510-516, August 2026.
Abstract Purpose To analyse the frequency and type of coexisting systemic disorders in children operated on for cataract in Sweden. Methods Data were retrieved from the Swedish National Pediatric Cataract Register (PECARE) for children operated between January 1, 2007, and December 31, 2023 (n = 975), including follow‐ups at age 1, 2, 5 and 10 ...
David Wackerberg, Jenny Gyllén, Birgitte Haargaard, Alf Nyström, Arzu Karatepe Hashas, Anna Linnarsson Wiklund, Eric Trocmé, Ulrika Kjellström, Kristina Tornqvist, Gunilla Magnusson   +9 more
wiley   +1 more source

Antibody characteristics, manufacturers, dilutions and protocol specifications for immunohistochemistry.

, 2014
CPS1, carbamoyl phosphate synthetase 1; OTC, ornithine carbamoyltransferase; ASS1, argininosuccinate synthetase; ASL, argininosuccinate lyase; ARG1, arginase; GLUL, glutamate–ammonia ligase; ABD, antibody diluent (DAKO); PBS, Phosphate-buffered saline ...
Giora van Straten (580550), Frank C. P. Holstege (117137), Robert P. Favier (144780), Marian J. A. Groot Koerkamp (117136), Frank G. van Steenbeek (194928), Hille Fieten (144796), Ingrid H. van Gils (580551), Guy C. M. Grinwis (165277), Bart Spee (66184), Jan Rothuizen (66188), Anne Kummeling (381713)   +10 more
core   +1 more source

Argininosuccinate neurotoxicity and prevention by creatine in argininosuccinate lyase deficiency: an in vitro study in rat 3D organotypic brain cell cultures. [PDF]

, 2019
The urea cycle disorder (UCD) argininosuccinate lyase (ASL) deficiency, caused by a defective ASL enzyme, exhibits a wide range of phenotypes, from life-threatening neonatal hyperammonemia to asymptomatic patients, with only the biochemical marker ...
Damian Hertig, Diez-Fernandez, Carmen, Diez-Fernandez, C., Nuoffer, J.M., Loup, Marc, Henry, Hugues, Hertig, Damian, Braissant, O., Henry, H., Marc Loup, Olivier Braissant, Diserens, G., Loup, M., Braissant, Olivier; https://orcid.org/, Häberle, Johannes, Carmen Diez‐Fernandez, Diserens, Gaëlle, Vermathen, Peter, Johannes Häberle, Braissant, Olivier, Peter Vermathen, Hugues Henry, Jean‐Marc Nuoffer, Hertig, D., Vermathen, P., Nuoffer, Jean-Marc, Häberle, J., Gaelle Diserens, Diez-Fernandez C, Diserens G, Häberle J, Vermathen P, Hertig D, Loup M, Braissant O, Nuoffer JM, Henry H   +36 more
core   +3 more sources

Effects of Dietary Sodium Butyrate on Growth Performance, Digestive Ability, Blood Biochemistry, and Ammonia Tolerance of Largemouth Bass (Micropterus salmoides)

Fishes
The aim of this study was to investigate the effects of sodium butyrate (SB) on growth performance, digestive ability, blood health, and ammonia tolerance of largemouth bass.
Xuan Chen, Wu Chen, Yanjie Tang, Muzi Zhang, Ming Li   +4 more
doaj   +1 more source

Crystallization and preliminary X-ray analysis of argininosuccinate lyase fromStreptococcus mutans

, 2011
Argininosuccinate lyase (ASL) is an important enzyme in arginine synthesis and the urea cycle, which are highly conserved from bacteria to eukaryotes.
Yan-Li Cao, Cao, Yan Li, Gui-Lan Li, Kai-Tuo Wang, Li, Gui Lan, Lan-Fen Li, Wang, Kai Tuo, Hong-Yin Zhang, Li, Lan Fen, Zhang, Hong Yin   +9 more
core   +1 more source

An assay for argininosuccinate synthetase in Neurospora [PDF]

, 1965
An assay for argininosuccinate synthetase in ...
Fairley, J. L., J. L. Fairley, Wampler, D. E., D. E. Wampler   +3 more
core   +1 more source