Results 121 to 130 of about 136,763,171 (336)

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Extending science instruction beyond the CER: Use of critical questions in the argumentation of middle school science students

Critiquing arguments is important for K-12 science students to learn but not emphasized by the predominant claim-evidence-reasoning (CER) argumentation model.
Nussbaum, E. Michael, Dove, Ian J., Herrera, Alicia N., Putney, LeAnn G., VanWinkle, M.S., Perera, Harsha N., Carroll, Kristoffer R., Tian, Lixian, Huerta, Margarita   +8 more
core   +1 more source

The influence of explicit nature of science and argumentation instruction on preservice primary teachers’ views of nature of science

, 2010
: There exists a general consensus in the science education literature around the goal of enhancing learners ’ views of nature of science (NOS). An extensive body of research in the field has highlighted the effectiveness of explicit NOS instructional ...
Christine V. Mcdonald, McDonald, CV
core   +1 more source

Observing Primary School Pre-service Teachers’ Oral Argumentation in Science Writing Heuristic Implementation

e-Kafkas Eğitim Araştırmaları Dergisi
This study provides information on primary school pre-service teachers’ (PST) oral argumentation in science writing heuristic (SWH) implementation. The study lasted six weeks and 34 PST participated in the study.
Berk Gümüş, Mehmet Şen
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Theory of argumentation in financial markets [PDF]

This paper aims to explore the relevance of the Theory of Argumentation TA in the complex area of financial reporting. Specifically, we investigated the scope of the phenomenon of persuasion in advertising.
Estrada, Fernando
core  

Synergizing PBL–SETS and e-worksheets: Enhancing conceptual understanding and scientific argumentation skills in science education

Assimilation
This study addresses a gap in science education research where problem-based learning (PBL) is often implemented separately, while its integration with the Science-Environment Technology-Society (SETS) approach and E-worksheet support to ...
Isna Atmim Nur Ana, Rizki Nor Amelia
doaj   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source