Results 91 to 100 of about 54,707 (265)

Ontological Foundations for Scholarly Debate Mapping Technology [PDF]

open access: yes, 2008
Mapping scholarly debates is an important genre of what can be called Knowledge Domain Analytics (KDA) technology – i.e. technology which combines both quantitative and qualitative methods of analysing specialist knowledge domains.
Benn, Neil   +3 more
core  

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Discursos de embajada en la épica: una propuesta de análisis argumentativo

open access: yesRevista de Lenguas Modernas, 2018
El artículo propone un modelo de análisis argumentativo que combina elementos de la retórica griega, la lógica india y la teoría de la argu- mentación.
Roberto Morales Harley
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Argumentation schemes as a way of arguments studies

open access: yesPhilosophy Journal, 2021
The paper investigates argument (argumentation) schemes that are used in the theory of argumentation for analyzing everyday reasoning. Such schemes should be understood as structures representing the most general types of argument. Today they are studied not only from theoretical perspectives but also in relation to their application in education and ...
openaire   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Analyzing Argumentation In Rich, Natural Contexts

open access: yesInformal Logic, 2008
The paper presents the theoretical and methodological aspects of research on the development of argument- ation in elementary school children. It presents a theoretical framework detailing psychological mechanisms responsible for the acquisition and ...
Anita Reznitskaya, Richard C. Anderson
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

GENERATORS OF UNIVERSALITY – ARGUMENTATION SCHEMES USED IN THE GULF WAR DEBATE

open access: yesBanber Erevani Hamalsarani. Sots'iologia, 2013

Andreas Göttlich
doaj   +1 more source

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