Results 81 to 90 of about 54,796 (286)

Argumentative Scheme for Abduction

open access: yesDiscourse, 2023
Introduction. The paper scrutinizes abduction through the lens of the argumentation theory. Abduction is treated as an argument with a special argumentative scheme. Argumentation schemes are seen as stereotypical patterns of common types of arguments used in everyday discourse.
openaire   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Des paradoxaux aux schémas argumentatifs

open access: yesCorela, 2014
This article aims to develop Carel’s view on ‘paradoxical’ utterances, based on two fundamental notions of the Theory of Semantic Blocks, ‘argumentative sequence’ and ‘argumentation scheme’.
Kohei Kida
doaj   +1 more source

Pushing the bounds of rationality: Argumentation and extended cognition [PDF]

open access: yes, 2016
One of the central tasks of a theory of argumentation is to supply a theory of appraisal: a set of standards and norms according to which argumentation, and the reasoning involved in it, is properly evaluated.
Godden, David
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Teaching as Abductive Reasoning: The Role of Argumentation

open access: yesInformal Logic, 2018
The view that argumentation is a desired reasoning practice in the classroom is well reported in the literature. Nonetheless, it is still not clear what type of reasoning supports classroom argumentation.
Chrysi Rapanta
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Persuasive argumentation as a cultural practice [PDF]

open access: yes, 2014
In this article author traces relation between argumentation and cultural practice. The first part focuses on definition of argumentation in informal logic tradition.
GAŁKOWSKI, Paweł
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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