Results 31 to 40 of about 17,975 (292)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Transparent Rational Decisions by Argumentation [PDF]

open access: yes, 2013
There is a well-documented indication that several applications would benefit from the transparency afforded by argumentation to support decision-making where standard decision theory is not useful, e.g. in healthcare.
Craven, Robert   +5 more
core  

Epistemic Normativity, Argumentation, and Fallacies [PDF]

open access: yes, 1997
In Biro and Siegel (1992) we argued that a theory of argumentation mustfully engage the normativity of judgments about arguments, and we developedsuch a theory.
Biro, John, Siegel, Harvey
core   +1 more source

L’argumentation sur la titulature impériale dans la dynastie Ming au prisme de la « Théorie généralisée de l’argumentation »

open access: yesArgumentation et Analyse du Discours, 2020
By using the Generalized Argumentation Theory, this paper tries to reveal the rules and structures of the argumentation about the imperial title issue in the Great Ritual Controversy. Our analysis shows that both the protagonist and the antagonist follow
Ju Shi’er, Liu Wen, Chen Zhixi
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Toward the Definition of Multimodal Argumentation [PDF]

open access: yesFuture Human Image, 2020
Argumentation theory is a crucial discipline for the development of the modern world. It provides innovative ways of evolution in interdisciplinary studies.
Kateryna Bura
doaj   +1 more source

Formal verification of debates in argumentation theory [PDF]

open access: yesProceedings of the 35th Annual ACM Symposium on Applied Computing, 2020
Humans engage in informal debates on a daily basis. By expressing their opinions and ideas in an argumentative fashion, they are able to gain a deeper understanding of a given problem and in some cases, find the best possible course of actions towards resolving it.
Ria Jha   +2 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Argumentation and explanation in the law

open access: yesFrontiers in Artificial Intelligence, 2023
This article investigates the conceptual connection between argumentation and explanation in the law and provides a formal account of it. To do so, the methods used are conceptual analysis from legal theory and formal argumentation from AI.
Antonino Rotolo   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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