Results 41 to 50 of about 17,975 (292)

Virtue and argument: Taking character into account [PDF]

, 2013
In this paper we consider the prospects for an account of good argument that takes the character of the arguer into consideration. We conclude that although there is much to be gained by identifying the virtues of the good arguer and by considering the ...
Justine Kingsbury, Kingsbury, Justine, Tracy Bowell, Bowell, Tracy   +3 more
core   +1 more source

Bioethical Decision Making and Argumentation Foreword [PDF]

, 2020
This book clarifies the meaning of the most important and pervasive concepts and tools in bioethical argumentation (principles, values, dignity, rights, duties, deliberation, prudence) and assesses the methodological suitability of the main methods for ...
Serna, Pedro
core   +1 more source

Teachers' Perceptions of Physics Scientific Argumentation Test Instruments Based on Modern Test Theory Using Question Modeling Through E-Learning Edpuzzle LMS

Indonesian Journal of Science and Mathematics Education, 2023
The study aims to understand teachers' perceptions of scientific argumentation test instruments in physics based on modern test theory using question modelling through Edpuzzle LMS e-learning.
Alda Novita Sari, Viyanti Viyanti, Chandra Ertikanto   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Reflections on the Physical or Visceral Mode of Argumentation in Michael Gilbert’s Theory of Multi-Modal Argumentation and its Relation to Gesture Studies and The Embodied Mind

Informal Logic, 2022
 In this paper I question the primacy of argumentation relying solely on logic by showing how the body and mind are deeply connected and as a result how communication and argumentation are a product of this mind/body connection. In particular, I explore
Claudio Duran
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Argumentation over Ontology Correspondences in MAS [PDF]

, 2007
In order to support semantic interoperation in open environments, where agents can dynamically join or leave and no prior assumption can be made on the ontologies to align, the different agents involved need to agree on the semantics of the terms used ...
Trevor Bench-Capon, Terry Payne, Payne, Terry R., Euzenat, Jerome, Payne, Terry, Bench-Capon, Trevor, Ian Blacoe, Jerôme Euzenat, Loredana Laera, Tamma, Valentina, Valentina Tamma, Laera, Loredana, Blacoe, Ian   +12 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

On the problem of bias in political argumentation: an investigation into discussions about political asylum in Germany and Austria [PDF]

, 1997
Kienpointner M, Kindt W. On the problem of bias in political argumentation: an investigation into discussions about political asylum in Germany and Austria. Journal of Pragmatics.
Kindt, Walther, Kienpointner, Manfred
core   +2 more sources

Analogical Argument Schemes and Complex Argument Structure

Informal Logic, 2015
This paper addresses several issues in argumentation theory. The over-arching goal is to discuss how a theory of analogical argument schemes fits the pragma-dialectical theory of argument schemes and argument structures, and how one should properly ...
Andre Juthe
doaj   +3 more sources