Results 41 to 50 of about 6,594 (258)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Argomentazioni Analogiche e Processi di Categorizzazione nella Diagnosi Nosologica

Rivista Internazionale di Filosofia e Psicologia, 2018
The purpose of this work is to provide a philosophical-cognitive explanation of nosological diagnosis by linking the classical philosophical themes of scientific reasoning (such as induction, deduction, abduction, analogy) to cognitive aspects of common ...
Francesco Gagliardi
doaj   +1 more source

Strategic Manoeuvering in 2019 Campaign Speeches in the Eastern Cape Province in South Africa: Extended Pragma-Dialectical Perspective

Modern Africa, 2023
This article investigates how political candidates in the Eastern Cape Province in South Africa employed means of strategic manoeuvring during the provincial election campaigns of 2019.
Zameka Paula Sijadu, Gaspardus Mwombeki
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Michael A. Gilbert: Not arguing logically is not illogical: Other ways of communicating arguments

Argumentation et Analyse du Discours
Michael A. Gilbert has contributed significantly to the field of contemporary Argumentation Theory. Most notable are his multi-modal theory of argumentation and coalescent argumentation, models of argument that he developed to address how interlocutors ...
Michael A. Gilbert, Linda Carozza
doaj   +1 more source

Introduction: The Epistemological Approach to Argumentation--A Map

Informal Logic, 2005
An overview of the epistemological approach to argumentation, explaining what it is, justifying it as better than a rhetorical or a consensual ist approach. systematizing the main directions and theories according to their criteria for good argumentation
Christoph Lumer
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Teisinis samprotavimas: argumentacinis metodologinis požiūris

Teisė, 2009
Teisinis argumentavimas, samprotavimas, teisės aiškinimas – susiję, sutampantys, o kartais tapatinami teise grįsto sprendimo priėmimo proceso aspektai. Lietuviškoje teisės doktrinoje plačiau analizuojama teisės aiškinimo, interpretavimo problematika, o ...
Eglė Mackuvienė
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

A World of Difference: The Rich State of Argumentation Theory

Informal Logic, 1995
This paper surveys the contributions to the study of argumentation in the two decades since the work of Toulmin and Perelman. Developments include Radical Argumentativism (Anscombre and Ducot), Communication and Rhetoric (American Speech Communication ...
Frans H. van Eemeren
doaj   +1 more source