Results 61 to 70 of about 245,470 (327)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
A Simple Theory of Argument Schemes
Informal Logic, 2021 While there has been in depth discussion of many particular argumentation schemes, some lament that there is little to no theory underpinning the notion of an argumentation scheme. Here I shall argue against the utility of argument schemes, at least as a
Geoff Goddu
doaj
A World of Difference: The Rich State of Argumentation Theory
Informal Logic, 1995 This paper surveys the contributions to the study of argumentation in the two decades since the work of Toulmin and Perelman. Developments include Radical Argumentativism (Anscombre and Ducot), Communication and Rhetoric (American Speech Communication ...
Frans H. van Eemeren
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Improved Answer-Set Programming Encodings for Abstract Argumentation
, 2015 The design of efficient solutions for abstract argumentation problems is a crucial step towards advanced argumentation systems. One of the most prominent approaches in the literature is to use Answer-Set Programming (ASP) for this endeavor. In this paper,
Gaggl, Sarah A. +4 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Review of: "Climate Change Denial Theories, Skeptical Arguments, and the Role of Science Communication" [PDF]
Russell Paterson
+8 more sources
On Realizing External Arguments: A Syntactic and Implicature Theory of the Disjointness Effect for Passives in Adult and Child Grammar [PDF]
, 2023 Loes Koring +3 more
openalex +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Is “Argument” subject to the product/process ambiguity?
Informal Logic, 2011 The product/process distinction with regards to “argument” has a longstanding history and foundational role in argumentation theory. I shall argue that, regardless of one’s chosen ontology of arguments, arguments are not the product of some process of ...
Geoff Goddu
doaj +1 more source