Results 61 to 70 of about 6,787,949 (343)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Argumentation update in YALLA (Yet Another Logic Language for Argumentation) [PDF]

, 2016
International audienceThis article proposes a complete framework for handling the dynamics of an abstract argumentation system. This frame can encompass several belief bases under the form of several argumentation systems, more precisely it is possible ...
Bisquert, Pierre, Cayrol, Claudette, Dupin De Saint Cyr - Bannay, Florence, Lagasquie-Schiex, Marie-Christine   +3 more
core   +3 more sources

Allocation of arguments and evidence theory

Theoretical Computer Science, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Theory of argumentation in financial markets [PDF]

This paper aims to explore the relevance of the Theory of Argumentation TA in the complex area of financial reporting. Specifically, we investigated the scope of the phenomenon of persuasion in advertising.
Estrada, Fernando
core   +4 more sources

Argomentazioni Analogiche e Processi di Categorizzazione nella Diagnosi Nosologica

Rivista Internazionale di Filosofia e Psicologia, 2018
The purpose of this work is to provide a philosophical-cognitive explanation of nosological diagnosis by linking the classical philosophical themes of scientific reasoning (such as induction, deduction, abduction, analogy) to cognitive aspects of common ...
Francesco Gagliardi
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Introduction: The Epistemological Approach to Argumentation--A Map

Informal Logic, 2005
An overview of the epistemological approach to argumentation, explaining what it is, justifying it as better than a rhetorical or a consensual ist approach. systematizing the main directions and theories according to their criteria for good argumentation
Christoph Lumer
doaj   +1 more source

Strategic Manoeuvering in 2019 Campaign Speeches in the Eastern Cape Province in South Africa: Extended Pragma-Dialectical Perspective

Modern Africa, 2023
This article investigates how political candidates in the Eastern Cape Province in South Africa employed means of strategic manoeuvring during the provincial election campaigns of 2019.
Zameka Paula Sijadu, Gaspardus Mwombeki
doaj   +1 more source

The Soundness of Pragmatic Argumentation: Does the End Justify the Means? [PDF]

, 1997
This paper addresses a specific form of argumentation, pragmatic argumentation, in which a certain action, choice or decision is justified by referring to the favourable consequences of the action (and the unfavourable consequences of the alternative ...
Eveline, Feteris T
core   +1 more source